Evidence map›Paper›PMID 39408370›Full record

ReviewNutrients2024

The Effects of Collagen Peptides as a Dietary Supplement on Muscle Damage Recovery and Fatigue Responses: An Integrative Review.

Pedro Augusto Querido Inacio, Yasmin Salgado Mussel Gomes, Ana Julia Nunes de Aguiar, Pedro Sardinha Leonardo Lopes-Martins, Flávio Aimbire, Patrícia Sardinha Leonardo, Alberto Souza Sá Filho, Rodrigo Alvaro B Lopes-Martins

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  8. Aspartimide Formation and Its Prevention in Fmoc Chemistry Solid Phase Peptide Synthesis.Chembiochem : a European journal of chemical biology · 2025
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pedro Augusto Querido InacioLaboratory of Applied Neurosciences, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.ORCID 0000-0001-9354-1460
Yasmin Salgado Mussel GomesLaboratory of Biophotonics and Experimental Therapeutics, LABITEX, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.
Ana Julia Nunes de AguiarLaboratory of Applied Neurosciences, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.
Pedro Sardinha Leonardo Lopes-MartinsLaboratory of Biophotonics and Experimental Therapeutics, LABITEX, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.ORCID 0009-0007-8548-3150
Flávio AimbireTranslational Medicine, Federal University of São Paulo-UNIFESP, São José dos Campos P.O. Box 12247-014, SP, Brazil.ORCID 0000-0002-4290-541X
Patrícia Sardinha LeonardoLaboratory of Health Technologies, LATES, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.
Alberto Souza Sá FilhoLaboratory of Applied Neurosciences, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.
Rodrigo Alvaro B Lopes-MartinsLaboratory of Biophotonics and Experimental Therapeutics, LABITEX, Evangelical University of Goiás, UniEvangélica, Av. Universitária S/N, Anápolis P.O. Box 75083-515, GO, Brazil.ORCID 0000-0002-4533-1335

Funding

National Council for Scientific and Technological Development 07586/2023-5
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe oral administration of hydrolyzed collagen peptides is a scientifically validated intervention for enhancing skeletal muscle health and performance. This integrative review consolidates the evidence supporting the use of low molecular weight collagen peptides (2000-3500 daltons) for their superior bioavailability and absorption. Our objective was to review the effects of collagen peptide or hydrolyzed collagen supplementation on muscle damage, recovery, and construction related to physical exercise.

methodsA bibliographic search was conducted in major English-language databases, including PubMed/Medline, using terms like "Peptides Collagen and Damage" and "collagen peptides AND Soreness Muscle". This review followed PRISMA guidelines, with bias risk assessed via the PEDro scale. The inclusion criteria were (a) randomized clinical trials, (b) randomized studies in humans with a control or placebo group, (c) studies assessing muscle damage or delayed onset muscle soreness via physiological markers or strength performance tests, and (d) studies using hydrolyzed collagen or collagen peptides.

resultsInitially, 752 articles were identified. After applying the inclusion and exclusion criteria, including duplicate removal, eight articles with 286 participants were included. Of these, 130 participants received collagen peptide supplementation, while 171 received a placebo or control.

conclusionThis integrative review supports the potential of collagen peptide supplementation to mitigate muscle stress from acute strenuous resistance training. However, due to the methodological heterogeneity among the studies, further clinical trials are needed to clarify the mechanisms underlying muscle improvement with collagen supplementation.

Indexed as

CollagenDietary SupplementsMuscle, SkeletalMyalgiaAdultExerciseFemaleHumansMaleMuscle FatigueMuscle StrengthPeptidesRandomized Controlled Trials as TopicResistance TrainingCollagenPeptidescollagen peptideshydrolyzed collagenmuscle massmuscle recovery

Identifiers

PMID39408370
PMCPMC11478671

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.