Evidence map›Paper›PMID 39408277›Full record

ArticleNutrients2024

The Epidemiology and Clinical Management of Short Bowel Syndrome and Chronic Intestinal Failure in Crohn's Disease in Italy: An IG-IBD Survey.

Tommaso Pessarelli, Matilde Topa, Andrea Sorge, Nicoletta Nandi, Daniela Pugliese, Fabio Salvatore Macaluso, Ambrogio Orlando, Simone Saibeni, Andrea Costantino, Francesco Stalla and 5 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tommaso PessarelliDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-8817-144X
Matilde TopaDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0001-8761-1872
Andrea SorgeDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-0285-9949
Nicoletta NandiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-4450-2593
Daniela PuglieseOU Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7930-5402
Fabio Salvatore MacalusoIBD Unit, "Villa Sofia-Cervello" Hospital, Viale Strasburgo 233, 90146 Palermo, Italy.ORCID 0000-0001-5128-3846
Ambrogio OrlandoIBD Unit, "Villa Sofia-Cervello" Hospital, Viale Strasburgo 233, 90146 Palermo, Italy.
Simone SaibeniGastroenterology Unit, Rho Hospital, ASST Rhodense, 20017 Rho, Italy.ORCID 0000-0001-5677-2534
Andrea CostantinoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0003-4345-6051
Francesco StallaDepartment of Medical Sciences, University of Turin, 10124 Turin, Italy.
Valentina ZadroGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, Italy.
Lucia ScaramellaGastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-9460-3296
Maurizio VecchiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.
Flavio CaprioliDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.
Luca ElliDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-0873-0759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesLimited data exist on the epidemiology and clinical management of short bowel syndrome (SBS) and chronic intestinal failure (CIF) in Crohn's disease (CD). This study aimed to evaluate these aspects in Italy.

methodsMembers of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) were invited to complete a cross-sectional web survey. A subgroup analysis examined the influence of different clinical settings on SBS and CIF management in CD.

resultsA total of 47/128 (36.7%) IG-IBD centers participated. Among them, 31.9% were teduglutide (TED) prescribers, and 48.9% were academic centers. The median estimated prevalence of CIF among small bowel CD patients was 1%, and it was significantly higher in academic centers (2.0% [IQR 1-5%] vs. 0.13% [IQR 0-1%],

conclusionsThe estimated prevalence of CIF in CD patients with small bowel involvement in Italy is 1%. The diagnosis and management practices for SBS and CIF are suboptimal, and TED use is limited.

Indexed as

Crohn DiseaseShort Bowel SyndromeAdultChronic DiseaseCross-Sectional StudiesFemaleGastrointestinal AgentsHumansIntestinal DiseasesIntestine, SmallItalyMaleMiddle AgedPeptidesPrevalenceSurveys and QuestionnairesGastrointestinal AgentsPeptidesteduglutideintestinal failure in Crohn’s diseaseprevalence of short bowel in CrohnSBS in CDshort bowel syndrome in Crohn’s disease

Identifiers

PMID39408277
PMCPMC11478841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.