Evidence map›Paper›PMID 39408202›Full record

ArticleNutrients2024

Extra Virgin Olive Oil Reduces the Risk of Non-Alcoholic Fatty Liver Disease in Females but Not in Males: Results from the NUTRIHEP Cohort.

Rossella Donghia, Rossella Tatoli, Angelo Campanella, Giuseppe Losurdo, Alfredo Di Leo, Giovanni De Pergola, Caterina Bonfiglio, Gianluigi Giannelli

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rossella DonghiaNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0002-9140-673X
Rossella TatoliNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0002-7891-6057
Angelo CampanellaNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0002-5044-4625
Giuseppe LosurdoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0000-0001-7038-3287
Alfredo Di LeoSection of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0000-0003-2026-1200
Giovanni De PergolaNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0003-0020-3273
Caterina BonfiglioNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0002-8650-348X
Gianluigi GiannelliNational Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0002-5140-8060

Funding

Italian Ministry of Health Ricerca Corrente 2024 Ricerca Corrente 2023
6 · The paper itself

Abstract

backgroundNon-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. One way to resolve this reversible condition is by making dietary changes. Extra virgin olive oil (EVOO) is often associated with an improvement in this disease. The aim of this study was to explore the protective role of EVOO on NAFLD conditions, stratified by gender.

methodsThe study cohort included 1426 participants assessed in the second recall of the NUTRIHEP cohort (2014-2018), subdivided by gender and dividing the EVOO intake into quartiles of daily gram intake.

resultsThe results indicated a protective role of the last quartile of EVOO only for female subjects, OR = 0.43,

conclusionsThe protective role of EVOO is different between genders. This difference has not been explored in the literature, so we conclude that this is one of the few papers in the literature to evaluate a gender difference in the intestinal absorption of humans based on an epidemiological study.

Indexed as

Non-alcoholic Fatty Liver DiseaseOlive OilAdultCohort StudiesFemaleHumansMaleMiddle AgedRisk FactorsSex FactorsOlive Oilextra virgin olive oilgendernon-alcoholic fatty liver disease

Identifiers

PMID39408202
PMCPMC11478343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.