Evidence map›Paper›PMID 39408097›Full record

ArticleHealthcare (Basel, Switzerland)2024

Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors.

Alba Marcos-Delgado, Vicente Martín-Sánchez, Ana Molina-Barceló, Jessica Alonso-Molero, Beatriz Pérez-Gómez, Marina Pollán, Nuria Aragonés, María Ederra-Sanza, Guillermo Fernández-Tardón, Gemma Binefa and 9 more

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alba Marcos-DelgadoThe Research Group in Gene-Environment and Health Interactions, Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.ORCID 0000-0002-7852-1282
Vicente Martín-SánchezThe Research Group in Gene-Environment and Health Interactions, Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.ORCID 0000-0003-0552-2804
Ana Molina-BarcelóCancer and Public Health Area, FISABIO-Public Health, 46022 Valencia, Spain.
Jessica Alonso-MoleroCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0002-1939-8798
Beatriz Pérez-GómezCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0002-4299-8214
Marina PollánCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.
Nuria AragonésCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0003-0983-2156
María Ederra-SanzaCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.
Guillermo Fernández-TardónCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.
Gemma BinefaCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0003-4652-0100
Victor MorenoCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0002-2818-5487
Rocío Barrios-RodríguezCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0002-8772-636X
Pilar AmianoCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.
José María HuertaCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0002-9637-3869
Enrique Pastor TesoServicio de Cirugía General y del Aparato Digestivo, Complejo Asistencial Universitario de León, 24008 León, Spain.
Juan AlguacilCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0003-2703-9725
Gemma Castaño-VinyalsCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.ORCID 0000-0003-4468-1816
Manolis KogevinasCIBER Epidemiology and Public Health CIBERESP, 28029 Madrid, Spain.
Antonio José Molina de la TorreThe Research Group in Gene-Environment and Health Interactions, Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.ORCID 0000-0002-5948-6397

Funding

ISCIII PI15/01032 , PS09/2078, PI12/00265.ISCIII-FEDER PI08/1770, PI08/0533, PS09/01286-LeónJunta de Andalucía PI-0571(2010)Junta de Castilla y León LE22A10-2
6 · The paper itself

Abstract

The aim of our study is to evaluate the relationship between sociodemographic and clinical characteristics of individuals with Colorectal Cancer (CRC), tumour-intrinsic characteristics and treatment received with health-related quality of life (HRQoL).

methodsCross-sectional analysis of data from 805 survivors from the MCC study was conducted. HRQoL was assessed through a general and specific questionnaire, SF-12 and FCSI (Colorectal Symptom Index). Statistical analyses were performed with linear regression with adjustment for sociodemographic variables, stage at diagnosis and histological grade.

resultsParticipants had survived a median of 7.9 years from diagnosis (IQR 7.1-8.5 years). Age at diagnosis, sex and area showed a clear association with HRQoL in both physical and mental dimensions of the SF-12 questionnaire. A direct association between CRC recurrence was also found in the PCS-12 and MCS-12 dimensions and radical surgery in the PCS-12. Regarding the scores in FCSI questionnaire, statistically significant differences were observed by sex, age and area, with older women being the most impaired (

conclusionsAge, sex and area was associated with lower scores of HRQoL among CRC survivors. Knowing the determinants related to HRQoL would allow us to lay the groundwork to develop strategies that help reduce morbidity and mortality, relapses and increase HRQoL.

Indexed as

cancer survivorscolorectal cancerhealth-related quality of life (HRQoL)

Identifiers

PMID39408097
PMCPMC11475455

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.