Evidence map›Paper›PMID 39408039›Full record

ReviewJournal of clinical medicine2024

The Role of Hypertension in Cognitive Dysfunction.

Panagiotis Theofilis, Georgia Doumani, Georgia-Christina Tsatsani, Nikolaos Volis, Aikaterini Kampourelli, Vasileios Thimis, Eleni Xanthopoulou, Rigas Kalaitzidis

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Review
  4. Article
  5. Article
  6. The role of per- and polyfluoroalkyl substances in cognitive impairment and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Panagiotis TheofilisHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.ORCID 0000-0001-9260-6306
Georgia DoumaniHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.
Georgia-Christina TsatsaniHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.
Nikolaos VolisHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.
Aikaterini KampourelliHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.
Vasileios ThimisHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.ORCID 0009-0002-6287-4160
Eleni XanthopoulouHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.
Rigas KalaitzidisHypertension Excellence Center, Center for Nephrology "G. Papadakis", General Hospital of Nikea-Piraeus "Ag. Panteleimon", 184 54 Nikea, Greece.ORCID 0000-0002-7773-7575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment and subsequent dementia are considered significant health challenges. In patients with established dementia, it is argued that hypertension is the main risk factor for small vessel ischemic disease and additional cortical white matter lesions. Cognitive domains and impairments associated with hypertension include learning, memory, attention, abstract reasoning, mental flexibility, psychomotor skills, and executive function. It is uncontrolled hypertension in midlife-but not late life-that is associated with worse cognitive impairment. Advanced imaging techniques confirm the effect of uncontrolled hypertension in developing dementia. Functional changes in the arterial system and an increase in arterial stiffness could be involved in the onset of dementia. In most studies, it is argued that better blood pressure control and duration of antihypertensive medication are associated with the incidence of dementia. In this review, the available data on the relationship between cognitive dysfunction and hypertension are examined.

Indexed as

antihypertensive therapycognitive functioncognitive impairmentdementiahypertension

Identifiers

PMID39408039
PMCPMC11478064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.