Evidence map›Paper›PMID 39407830›Full record

ReviewJournal of clinical medicine2024

Neoadjuvant Treatment in Locally Advanced Thyroid Carcinoma.

Víctor Navas Moreno, Fernando Sebastián Valles, Marcos Lahera Vargas, Berta Hernández Marín, Elena Carrillo López, Mónica Marazuela, José Luis Muñoz de Nova

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Surgical treatment for patients with papillary thyroid carcinoma invading the cervical trachea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Víctor Navas MorenoDepartment of Endocrinology and Nutrition, Hospital Universitario de La Princesa, 28028 Madrid, Spain.
Fernando Sebastián VallesDepartment of Endocrinology and Nutrition, Hospital Universitario de La Princesa, 28028 Madrid, Spain.ORCID 0000-0002-4127-0483
Marcos Lahera VargasDepartment of Endocrinology and Nutrition, Hospital Universitario de La Princesa, 28028 Madrid, Spain.
Berta Hernández MarínInstituto de Investigación Sanitaria Princesa (IIS-IP), 28028 Madrid, Spain.
Elena Carrillo LópezDepartment of Endocrinology and Nutrition, Hospital Universitario de La Princesa, 28028 Madrid, Spain.ORCID 0009-0004-5642-677X
Mónica MarazuelaDepartment of Endocrinology and Nutrition, Hospital Universitario de La Princesa, 28028 Madrid, Spain.ORCID 0000-0003-1158-9618
José Luis Muñoz de NovaInstituto de Investigación Sanitaria Princesa (IIS-IP), 28028 Madrid, Spain.ORCID 0000-0003-1439-5632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the focus in the last decades has been on the overdiagnosis of incidentally detected thyroid carcinomas in early stages, the other extreme of the disease is represented by locally advanced tumors with the invasion of neighboring structures. These are infrequent tumors, but they have a high complexity and a poor prognosis. In the absence of effective therapies allowing preoperative tumor reduction, in order to achieve a more restricted surgery, treatment was limited to aggressive surgery with resection of the aerodigestive tract and major vascular structures or palliative treatment. However, due to the increased knowledge of tumor biology and the results that tyrosine kinase inhibitors have achieved in the treatment of radioactive iodine-refractory tumors, neoadjuvant therapy with a curative intent has emerged as a reality to be taken into account when dealing with these patients. This paper presents a narrative review of the current scientific evidence regarding neoadjuvant treatment in locally advanced thyroid cancer.

Indexed as

advanced thyroid cancerneoadjuvant treatmenttargeted therapiesthyroid cancerthyroidectomy

Identifiers

PMID39407830
PMCPMC11477333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.