Evidence map›Paper›PMID 39407828›Full record

ArticleJournal of clinical medicine2024

Improving Therapy for Children with Scoliosis through Reducing Ionizing Radiation by Using Alternative Imaging Methods-A Study Protocol.

Fee Keil, Robert Schneider, Nenad Polomac, Omar Zabar, Tobias Finger, Fabian Holzgreve, Marcus Czabanka, Christina Erbe, David A Groneberg, Elke Hattingen and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fee KeilInstitute of Neuroradiology, Goethe University Hospital, 60528 Frankfurt, Germany.ORCID 0000-0002-9158-1538
Robert SchneiderInstitute of Occupational, Social, Environmental Medicine, Goethe University, 60596 Frankfurt, Germany.
Nenad PolomacInstitute of Neuroradiology, Goethe University Hospital, 60528 Frankfurt, Germany.
Omar ZabarInstitute of Occupational, Social, Environmental Medicine, Goethe University, 60596 Frankfurt, Germany.
Tobias FingerDepartment of Neurosurgery, Goethe University Hospital, 60596 Frankfurt, Germany.
Fabian HolzgreveInstitute of Occupational, Social, Environmental Medicine, Goethe University, 60596 Frankfurt, Germany.ORCID 0000-0002-1115-131X
Marcus CzabankaDepartment of Neurosurgery, Goethe University Hospital, 60596 Frankfurt, Germany.
Christina ErbeDepartment of Orthodontics, Johannes Gutenberg University Hospital, Mainz, 55131 Mainz, Germany.ORCID 0000-0003-1950-640X
David A GronebergInstitute of Occupational, Social, Environmental Medicine, Goethe University, 60596 Frankfurt, Germany.
Elke HattingenInstitute of Neuroradiology, Goethe University Hospital, 60528 Frankfurt, Germany.ORCID 0000-0002-8392-9004
Daniela OhlendorfInstitute of Occupational, Social, Environmental Medicine, Goethe University, 60596 Frankfurt, Germany.
Panagiotis DiaremesClinic for Orthopaedics, Goethe University Hospital, 60596 Frankfurt, Germany.ORCID 0000-0003-1569-8328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with scoliosis often require multiple imaging modalities. The aim of this study was to find out whether primary diagnosis, including surgical planning, could be carried out entirely without computed tomography (CT) scans and whether follow-up could be replaced with alternative methods without the use of X-rays. In order to reduce the radiation exposure in the diagnosis and treatment of severe scoliosis, we expect to replace X-rays with radiation-free or less-intensive radiation examinations. This study protocol is interdisciplinary.

methodsA total of 50 male and female patients (children and adolescents, aged 7-18 years) treated for scoliosis will be analyzed. In addition to routine projection radiographs, preoperative CT, and/or X-ray stereoradiography (EOS) examinations, thin-slice 3D magnetic resonance imaging (MRI) sequences will be retrospectively reformatted during the preoperative MRI examination. A three-dimensional back scan (video-raster stereography) and an intraoral scan will also be obtained. The following questions should be answered at the end of the project: (1) Can MRI examination with additional thin-slice 3D reconstruction answer all relevant questions for preoperative planning instead of CT? (2) Are EOS or whole-spine X-ray examinations in combination with MRI data sufficient for the evaluation of the pedicles and spinal deformity? (3) Does the Cobb angle in the radiograph correlate with the calculations from the back scanner image and can follow-up checks be replaced? (4) Are there any correlations between dental anomalies and scoliosis?

conclusionsUntil now, pediatric patients with scoliosis have been diagnosed, monitored, and treated with numerous independent specialist disciplines, such as pediatricians, orthopedic surgeons, neurosurgeons, and general practitioners with different radiological issues. The aim of this project is to reduce radiation and lower perioperative risks by creating a preoperative and follow-up-related standard protocol in close interdisciplinary and targeted cooperation between all the specialist disciplines involved. In line with the holistic examination approach, the associated accompanying diseases and developmental disorders such as dental and neuronal malformations will also be examined. On the one hand, CT-based questions could be replaced with the reconstruction of thin-slice MRI sequences. In addition, it may be possible to use the three-dimensional back scan as an intermediate diagnostic procedure instead of X-rays in the monitoring of severe scoliosis. Insofar as correlations or causalities between scoliosis and occlusal anomalies, early orthodontic intervention could positively benefit the duration of therapy at a later stage.

Indexed as

follow-upinterdisciplinary teampediatric radiation protectionradiation exposurescoliosis preoperative standardvideo-raster stereography

Identifiers

PMID39407828
PMCPMC11476651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.