Evidence map›Paper›PMID 39407816›Full record

ReviewJournal of clinical medicine2024

Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin's Lymphoma: A Case Report and Review of the Literature.

Daniela Estefania Banegas, Alessia Moioli, Eleonora Santoni, Erica Tagliavini, Francesca Maria Quaglia, Andrea Bernardelli, Carlo Visco

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniela Estefania BanegasHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.
Alessia MoioliHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.
Eleonora SantoniHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.
Erica TagliaviniHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.
Francesca Maria QuagliaHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.ORCID 0000-0003-4347-3775
Andrea BernardelliHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.
Carlo ViscoHematology Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, Verona University, 37134 Verona, Italy.ORCID 0000-0003-2863-0883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 43-year-old Caucasian man who developed visceral leishmaniasis (VL) following treatment with a combination of brentuximab vedotin and doxorubicin, vinblastine, and dacarbazine (A+AVD) for advanced-stage classical Hodgkin's lymphoma (cHL). The patient initially showed a favorable response to the treatment, but shortly after completing six cycles, he experienced recurrent fever, splenomegaly, and severe anemia. Extensive infectious disease evaluations led to a diagnosis of VL, confirmed by PCR testing. The patient was treated with amphotericin B, resulting in full clinical recovery. In addition to presenting this rare case, we conducted a full review of the literature on VL in the context of hematological disorders, including non-Hodgkin's lymphoma, splenic marginal zone lymphoma, and other lymphoproliferative diseases. This review highlights the increasing prevalence of VL in immunocompromised individuals, particularly those undergoing treatments like chemotherapy or immunotherapy, and underscores the importance of considering VL in differential diagnoses when such patients present with persistent fever and splenomegaly.

Indexed as

A+AVDbrentuximab–AVDHodgkin’s lymphomasplenomegalyvisceral leishmaniasis

Identifiers

PMID39407816
PMCPMC11477309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.