Evidence map›Paper›PMID 39407561›Full record

ArticleMolecules (Basel, Switzerland)2024

Polyphosphoric Acid-Promoted Efficient Synthesis of Cinnamides via Aldol Condensation of Amide.

Enhua Wang, Lishou Yang, Lanfeng He, Qian Yang, Xue Wang, Yunlu Liu, Manxiang Li, Yang Lei, Xiaosheng Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Enhua WangDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Lishou YangState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Lanfeng HeState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Qian YangDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Xue WangDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Yunlu LiuDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Manxiang LiDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Yang LeiDepartment of Food and Medicine, Guizhou Vocational College of Agriculture, Qingzhen 551400, China.
Xiaosheng YangState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.ORCID 0000-0003-1535-3282

Funding

Guizhou Provincial Natural Science Foundation QKHJC-ZK[2024] General 643Innovation Capacity Construction of Scientific Research Institutions in Guizhou Province QKHFQ[2024]005Project of Key Laboratory for Characteristics of Colleges and Universities of Guizhou Provincial Department of Education QJHKYZ[2020]018Project of Natural Science Research of Guizhou Vocational College of Agriculture yk230109
6 · The paper itself

Abstract

Cinnamides are common core structures that exist in a great number of pharmaceuticals and natural products. The development of efficient methods for preparing cinnamides is in great need. We report herein an efficient polyphosphoric acid (PPA)-promoted direct aldol condensation of an amide for the convenient and straightforward preparation of cinnamides. A variety of cinnamides were obtained in moderate-to-excellent yields (65-89%). This strategy features the use of equivalent amides and a short reaction time.

Indexed as

aldol condensationamidecinnamidepolyphosphoric acid

Identifiers

PMID39407561
PMCPMC11477491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.