Evidence map›Paper›PMID 39407479›Full record

ReviewMolecules (Basel, Switzerland)2024

Extraction and Synthesis of Typical Carotenoids: Lycopene, β-Carotene, and Astaxanthin.

Yuxuan Jiang, Jingyi Ye, Yadong Hu, Jian Zhang, Wenhui Li, Xinghu Zhou, Mingzhou Yu, Yiyang Yu, Jingwei Yang, Wenge Yang and 3 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Development of Bacillus subtilis cell factories for nutraceuticals production.World journal of microbiology & biotechnology · 2026
    Review
  3. In Silico and In-vitro assessment of β carotene extracted from Westella botryoides for fighting multidrug resistant bacterial strains.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Antioxidants: a comprehensive review.Archives of toxicology · 2025
    Review
  12. Review
  13. Frontiers in microbiology · 2025
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuxuan JiangCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.
Jingyi YeCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Yadong HuJiangsu Innovation Center of Marine Bioresource, Jiangsu Coast Development Investment Co., Ltd., Nanjing 210019, China.
Jian ZhangCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Wenhui LiCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Xinghu ZhouJiangsu Innovation Center of Marine Bioresource, Jiangsu Coast Development Investment Co., Ltd., Nanjing 210019, China.
Mingzhou YuCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Yiyang YuCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Jingwei YangKey Laboratory of Coastal Salt Marsh Ecosystems and Resources, Ministry of Natural Resources, Nanjing 210006, China.
Wenge YangSchool of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China.
Jinchi JiangCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Jie CuiCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.ORCID 0000-0002-1344-1206
Yonghong HuCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.

Funding

Jiangsu Innovation Center of Marine Bioresource 2023YHTZZZ02Key Laboratory of Coastal Salt Marsh Ecosystems and Resources, Ministry of Natural Resources KLCSMERMNR2021002Marine science and Technology Innovation Project of Jiangsu Province JSZRHYKJ202210Marine science and Technology Innovation Project of Jiangsu Province JSZRHYKJ202309National Key Research and Development Program of China 2022YFD2101404Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX23_1490
6 · The paper itself

Abstract

Carotenoids are tetraterpene compounds acting as precursors to vitamin A, with functions that include protecting eyesight, enhancing immunity, promoting cell growth and differentiation, and providing antioxidative benefits. Lycopene, β-carotene, and astaxanthin are particularly critical for health and have diverse applications in food, health products, and medicine. However, natural carotenoids are encased within cell structures, necessitating mechanical methods to disrupt the cell wall for their extraction and purification-a process often influenced by environmental conditions. Thus, improving the efficiency of carotenoid extraction from natural resources is of great interest. This review delves into the research progress made on the extraction processes, structures, and biological functions of carotenoids, focusing on lycopene, β-carotene, and astaxanthin. Traditional extraction methods primarily involve organic solvent-assisted mechanical crushing. With deeper research and technological advancements, more environmentally friendly solvents, advanced machinery, and suitable methods are being employed to enhance the extraction and purification of carotenoids. These improvements have significantly increased extraction efficiency, reduced preparation time, and lowered production costs, laying the groundwork for new carotenoid product developments.

Indexed as

beta CaroteneLycopeneXanthophyllsCarotenoidsSolventsastaxanthinebeta CaroteneCarotenoidsLycopeneSolventsXanthophyllsastaxanthinbiosynthesiscarotenoidsextractionlycopeneβ-carotene

Identifiers

PMID39407479
PMCPMC11478001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.