Evidence map›Paper›PMID 39407469›Full record

ArticleMolecules (Basel, Switzerland)2024

Design and Synthesis of Pyridyl and 2-Hydroxyphenyl Chalcones with Antitubercular Activity.

Kelphina Aziafor, Ketan Ruparelia, Brandon Moulds, Mire Zloh, Tanya Parish, Federico Brucoli

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. TowardMicroorganisms · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelphina AziaforLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
Ketan RupareliaLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
Brandon MouldsLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
Mire ZlohFaculty of Pharmacy, University Business Academy, 21000 Novi Sad, Serbia.ORCID 0000-0002-4848-2737
Tanya ParishCenter for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA 98102, USA.
Federico BrucoliLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.ORCID 0000-0001-8661-2910

Funding

Seattle Tuberculosis Research Advancement CenterP30AI168034 · NIAID · UNIVERSITY OF WASHINGTON · PI Rhea N Coler, CHETAN SESHADRI · 2022 to 2026
$6.3M
NIAID NIH HHS P30 AI168034
6 · The paper itself

Abstract

A focussed library of pyridyl and 2-hydroxyphenyl chalcones were synthesized and tested for growth inhibitory activity against

Indexed as

Antitubercular AgentsChalconesMolecular Docking SimulationMycobacterium tuberculosisCell Line, TumorCell ProliferationDrug DesignHep G2 CellsHumansMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipAntitubercular AgentsChalconesbreast cancerchalconesclaisen condensationmycobacterium tuberculosisprotein tyrosine phosphatase B (Mbt PtpB)

Identifiers

PMID39407469
PMCPMC11478287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.