Evidence map›Paper›PMID 39407463›Full record

ArticleMolecules (Basel, Switzerland)2024

Antitumoral and Antiproliferative Potential of Synthetic Derivatives of Scorpion Peptide IsCT1 in an Oral Cavity Squamous Carcinoma Model.

Laertty Garcia de Sousa Cabral, Cyntia Silva de Oliveira, Vani Xavier Oliveira, Rosely Cabette Barbosa Alves, Jean-Luc Poyet, Durvanei Augusto Maria

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laertty Garcia de Sousa CabralFaculty of Medicine, University of Sao Paulo, Sao Paulo 05508-220, Brazil.ORCID 0000-0002-4586-2945
Cyntia Silva de OliveiraPaulista School of Medicine, Postgraduate Program in Molecular Biology, Federal University of São Paulo, Sao Paulo 04044-020, Brazil.ORCID 0000-0003-2049-7627
Vani Xavier OliveiraPaulista School of Medicine, Postgraduate Program in Molecular Biology, Federal University of São Paulo, Sao Paulo 04044-020, Brazil.ORCID 0000-0002-9420-0956
Rosely Cabette Barbosa AlvesLaboratory of Development and Innovation, Butantan Institute, Sao Paulo 05585-000, Brazil.
Jean-Luc PoyetINSERM UMRS976, Institut De Recherche Saint-Louis, Hôpital Saint-Louis, 75010 Paris, France.ORCID 0000-0002-3747-255X
Durvanei Augusto MariaFaculty of Medicine, University of Sao Paulo, Sao Paulo 05508-220, Brazil.

Funding

CAPES - Foundation Coordination for the Improvement of Higher Education Personnel 88887.630761/2021-00
6 · The paper itself

Abstract

The oral cavity is a frequent site for head and neck cancers, which rank as the sixth most common cancer globally, with a 5-year survival rate slightly over 50%. Current treatments are limited, and resistance to therapy remains a significant clinical obstacle. IsCT1, a membrane-active peptide derived from the venom of the scorpion

Indexed as

Antineoplastic AgentsCarcinoma, Squamous CellCell ProliferationMouth NeoplasmsScorpion VenomsAnimalsApoptosisCell CycleCell Line, TumorHumansMembrane Potential, MitochondrialPeptidesScorpionsAntineoplastic AgentsPeptidesScorpion Venomsanticancer peptideapoptosissquamous cell carcinomasynthetic peptidetongue cancer

Identifiers

PMID39407463
PMCPMC11478212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.