Evidence map›Paper›PMID 39407462›Full record

ArticleMolecules (Basel, Switzerland)2024

Hispidol Regulates Behavioral Responses to Ethanol through Modulation of BK Channels: A Novel Candidate for the Treatment of Alcohol Use Disorder.

Wooin Yang, Hee Jae Goh, Young Taek Han, Myon-Hee Lee, Dong Seok Cha

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wooin YangCollege of Pharmacy, Woosuk University, Wanju 55338, Republic of Korea.
Hee Jae GohCollege of Pharmacy, Woosuk University, Wanju 55338, Republic of Korea.
Young Taek HanCollege of Pharmacy, Dankook University, Cheonan 31116, Republic of Korea.
Myon-Hee LeeDivision of Hematology/Oncology, Department of Internal Medicine, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA.
Dong Seok ChaCollege of Pharmacy, Woosuk University, Wanju 55338, Republic of Korea.ORCID 0000-0002-0613-7687

Funding

National Research Foundation of South Korea NRF-2021R1F1A1047013
6 · The paper itself

Abstract

Alcohol use disorder (AUD) is the most common substance use disorder and poses a significant global health challenge. Despite pharmacological advances, no single drug effectively treats all AUD patients. This study explores the protective potential of hispidol, a 6,4'-dihydroxyaurone, for AUD using the

Indexed as

AlcoholismCaenorhabditis elegansEthanolLarge-Conductance Calcium-Activated Potassium ChannelsAnimalsBehavior, AnimalCaenorhabditis elegans ProteinsDisease Models, AnimalMiceCaenorhabditis elegans ProteinsEthanolLarge-Conductance Calcium-Activated Potassium Channelsslo-1 protein, C elegansalcohol use disorderBK channelethanol intoxicationhispidolwithdrawal

Identifiers

PMID39407462
PMCPMC11478065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.