Evidence map›Paper›PMID 39407419›Full record

ArticleJournal of cardiovascular electrophysiology2024

Combined left atrial appendage occlusion and catheter ablation procedure for left atrial arrhythmias: A real-world, propensity-matched analysis.

Stefan Preisendörfer, Muhammad T Ayub, Aakash Sheth, George Y Jabbour, Madhurmeet Singh, Chinmay P Patel, Hemal Gada, Aditya Bhonsale, Mehak Dhande, Nathan A Estes and 9 more

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Comparative outcomes of left atrial appendage occlusion with and without catheter ablation: a 5-year propensity-matched analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Stefan PreisendörferHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2320-5175
Muhammad T AyubHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Aakash ShethHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
George Y JabbourHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Madhurmeet SinghHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Chinmay P PatelHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Hemal GadaHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Aditya BhonsaleHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Mehak DhandeHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Nathan A EstesHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-5461-7247
Krishna KancharlaHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Dustin E KlinerHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Amber MakaniHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Aditi NaniwadekarHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Alaa ShalabyHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2000-7678
Virginia SinglaHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Andrew VoigtHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Samir F SabaHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-4669-803X
Sandeep K JainHeart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-5815-370X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReal-world studies comparing safety and efficacy of combined percutaneous left atrial appendage occlusion (LAAO) and catheter ablation (CA) to LAAO alone are limited.

methodsPatients from a large US hospital system undergoing combined LAAO and left-atrial CA from 8/2020 to 2/2024 were retrospectively analyzed and compared to a control group undergoing LAAO alone. Controls were identified using a 1:2 propensity score match based on LAAO device type (Watchman FLX vs. Amulet), CHA

resultsPatients were younger in the combined (n = 72) than in the control group (n = 144, 70.2 ± 7.3 vs. 76.7 ± 6.9 years, p < 0.001) but otherwise comparable with a mean CHA

conclusionThis large, real-world analysis indicates comparable safety and efficiency of combined LAAO and CA when compared with LAAO alone.

Indexed as

Atrial AppendageAtrial FibrillationCatheter AblationPropensity ScoreAction PotentialsAgedAged, 80 and overAtrial Function, LeftCardiac CatheterizationCombined Modality TherapyFemaleHeart RateHumansMaleMiddle AgedRetrospective Studiesatrial fibrillationcatheter ablationcombined procedureleft atrial appendage occlusionpulmonary vein isolation

Identifiers

PMID39407419
PMCPMC11650415

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.