Evidence map›Paper›PMID 39407244›Full record

ReviewGut pathogens2024

Unveiling the overlooked fungi: the vital of gut fungi in inflammatory bowel disease and colorectal cancer.

Yilin Huang, Yang Wang, Xiaotian Huang, Xiaomin Yu

Abstract readReview
In one paragraph

Review in Gut pathogens, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yilin HuangSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Yang WangSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Xiaotian HuangSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. xthuang@ncu.edu.cn.
Xiaomin YuSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. yuxiaomin@ncu.edu.cn.

Funding

The Double-Thousand Talent Program of Jiangxi Province jxsq2023201019The Jiangxi Natural Science Foundation 20232BAB216091, 20202BAB206062the National Natural Science Foundation of China NSFC 32260024, 32060040
6 · The paper itself

Abstract

The fungi of the human microbiota play important roles in the nutritional metabolism and immunological balance of the host. Recently, research has increasingly emphasised the role of fungi in modulating inflammation in intestinal diseases and maintaining health in this environment. It is therefore necessary to understand more clearly the interactions and mechanisms of the microbiota/pathogen/host relationship and the resulting inflammatory processes, as well as to offer new insights into the prevention, diagnosis and treatment of inflammatory bowel disease (IBD), colorectal cancer (CRC) and other intestinal pathologies. In this review, we comprehensively elucidate the fungal-associated pathogenic mechanisms of intestinal inflammation in IBD and related CRC, with an emphasis on three main aspects: the direct effects of fungi and their metabolites on the host, the indirect effects mediated by interactions with other intestinal microorganisms and the immune regulation of the host. Understanding these mechanisms will enable the development of innovative approaches based on the use of fungi from the resident human microbiota such as dietary interventions, fungal probiotics and faecal microbiota transplantation in the prevention, diagnosis and treatment of intestinal diseases.

Indexed as

Colorectal cancerFungusInflammatory bowel diseaseIntestinal inflammation

Identifiers

PMID39407244
PMCPMC11481806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.