Evidence map›Paper›PMID 39407227›Full record

ArticleJournal of nanobiotechnology2024

NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.

Yunxian Dong, Haibin Wang, Youliang Zhang, Yanqun Wu, Ling Lu, Hao Yu, Lingcong Zhou, Peng Zhao, Sixue Ouyang, Zibin Song and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yunxian Dong *Department of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Haibin Wang *Department of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Youliang Zhang *Department of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Yanqun WuDepartment of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Ling LuNMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Hao YuDepartment of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Lingcong ZhouDepartment of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China.
Peng ZhaoNMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Sixue OuyangSchool of Chemistry and Chemical Engineering, South China University of Technology, No. 381 Wushan Road, Guangzhou, 510640, China.
Zibin SongInstitute of Brain Diseases, Department of Neurosurgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Zhicheng HuDepartment of Burns, Wound Repair and Reconstruction, the First Affiliated Hospital of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, China.
Dongming LvDepartment of Burns, Wound Repair and Reconstruction, the First Affiliated Hospital of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, China.
Yanchao RongDepartment of Burns, Wound Repair and Reconstruction, the First Affiliated Hospital of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, China.
Zirui ZhaoDepartment of Burns, Wound Repair and Reconstruction, the First Affiliated Hospital of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, China.
Jia TaoSchool of Chemistry and Chemical Engineering, South China University of Technology, No. 381 Wushan Road, Guangzhou, 510640, China. cejtao@scut.edu.cn.
Bing TangDepartment of Burns, Wound Repair and Reconstruction, the First Affiliated Hospital of Sun Yat-sen University, No.58 Zhongshan Er Road, Guangzhou, 510080, China. tangbing@mail.sysu.edu.cn.
Shengkang LuoDepartment of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, No.466 Middle Xin Gang Road, Guangzhou, 510317, China. luoshk@gd2h.org.cn.

Funding

Postdoctoral Workstation Project of Guangdong Second Provincial General Hospital 2023BSGZ013
6 · The paper itself

Abstract

The hypertrophic scar (HS) is a prevalent cutaneous fibrotic disorder that impacts both the aesthetic and functional aspects of the skin, there is an urgent need for a highly safe and effective approach to address the challenge of HS with thick and deep types. Inspired by the superior deep tissue penetrative ability of near-infrared-II (NIR-II) light and potential mitochondria ROS inducing effect of Chinese medicine lycorine (LYC), we fabricated a Cu

Indexed as

AutophagyCicatrix, HypertrophicFibroblastsInfrared RaysReactive Oxygen SpeciesAnimalsApoptosisCopperDrugs, Chinese HerbalHumansMitochondriaNanoparticlesRabbitsCopperDrugs, Chinese HerbalReactive Oxygen SpeciesApoptosisAutophagyHypertrophic scarLycorinePhotothermal therapy

Identifiers

PMID39407227
PMCPMC11481805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.