Evidence map›Paper›PMID 39407013›Full record

ArticleInternational journal of obesity (2005)2025

Childhood maltreatment, adulthood obesity and incident type 2 diabetes: a retrospective cohort study using UK Biobank.

Tamta Nadaraia, Ed Whittaker, Indira Kenyon, Jirapitcha Boonpor, Ziyi Zhou, Shinya Nakada, Ike Dhiah Rochmawati, Carlos Celis-Morales, Joey Ward, Naja Hulvej Rod and 5 more

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In one paragraph

Article in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tamta NadaraiaSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Ed WhittakerSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0001-6394-0401
Indira KenyonNHS Greater Glasgow and Clyde, Glasgow, UK.
Jirapitcha BoonporSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Ziyi ZhouSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0002-8971-9614
Shinya NakadaSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Ike Dhiah RochmawatiSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Carlos Celis-MoralesSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.ORCID 0000-0003-2612-3917
Joey WardSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0003-0951-8511
Naja Hulvej RodCopenhagen Health Complexity Center, University of Copenhagen, Copenhagen, Denmark.
Jill P PellSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Helen MinnisSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Thomas HehlmannDepartment of Human and Health Sciences, University of Bremen, Bremen, Germany.ORCID 0000-0002-9267-8454
Frederick K HoSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK. Frederick.Ho@glasgow.ac.uk.ORCID 0000-0001-7190-9025
Daniel MackaySchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundThis study aims to explore the association of childhood maltreatment with obesity and type 2 diabetes (T2D) in adulthood, and whether obesity is a mediator of the latter.

methodsIn a retrospective cohort study using UK Biobank data, participants recalled childhood maltreatment. Linear regression, logistic regression, and Cox proportional hazard models were used to investigate the associations with body mass index (BMI), obesity, and T2D, adjusted for sociodemographic factors. Decomposition analysis was used to examine the extent to which T2D excess risk was attributed to BMI.

resultsOf the 153,601 participants who completed the childhood maltreatment questions, one-third reported some form of maltreatment. Prevalence of adult obesity and incidence of T2D were higher with the number of reported childhood maltreatment types. People who reported ≥3 types of childhood maltreatment were at higher risk of obesity (OR 1.55, 95% CI 1.47-1.63) and incident T2D (HR 1.65, 95% CI 1.52-1.80). Excess T2D risk among those reporting maltreatment could be reduced by 39% if their BMI was comparable to participants who had not been maltreated, assuming causality.

conclusionsPeople who recalled maltreatment in childhood are at higher risk of T2D in adulthood, partly due to obesity.

Indexed as

Diabetes Mellitus, Type 2ObesityAdultAdult Survivors of Child AbuseAgedBiological Specimen BanksBody Mass IndexChildChild AbuseFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk Factors

Identifiers

PMID39407013
PMCPMC11683003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.