Evidence map›Paper›PMID 39406998›Full record

ArticleMolecular psychiatry2025

Characterization of patients with major psychiatric disorders with AMPA receptor positron emission tomography.

Mai Hatano, Waki Nakajima, Hideaki Tani, Hiroyuki Uchida, Tomoyuki Miyazaki, Tetsu Arisawa, Yuuki Takada, Sakiko Tsugawa, Akane Sano, Kotaro Nakano and 25 more

Abstract read
In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Age and sex-dependent alteration in AMPA receptor density in living human brain.European journal of nuclear medicine and molecular imaging · 2026
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  10. First-in-Human Study ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Mai Hatano *Department of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Waki Nakajima *Department of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Hideaki Tani *Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Hiroyuki UchidaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-0628-7036
Tomoyuki MiyazakiDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tetsu ArisawaRadioisotope Research Center, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yuuki TakadaDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Sakiko TsugawaDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Akane SanoDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kotaro NakanoDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tsuyoshi EiroDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Hiroki AbeDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Akira SudaDepartment of Psychiatry, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Takeshi AsamiDepartment of Psychiatry, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Akitoyo HishimotoDepartment of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan.
Nobuhiro NagaiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Teruki KoizumiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Shinichiro NakajimaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-2601-2195
Shunya KurokawaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-6451-5263
Yohei OhtaniDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Kie TakahashiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Yuhei KikuchiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-4656-5763
Taisuke YatomiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Shiori HondaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Masahiro JinzakiDepartment of Radiology, Keio University School of Medicine, Tokyo, Japan.
Yoji HiranoDepartment of Psychiatry, Division of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.ORCID 0000-0001-6847-9677
Ryo MitomaDepartment of Neuropsychiatry, Graduate School of Medical Sciences, Kyusyu University, Fukuoka, Japan.
Shunsuke TamuraDepartment of Psychiatry, Division of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Shingo BabaDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyusyu University, Fukuoka, Japan.
Osamu TogaoDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyusyu University, Fukuoka, Japan.
Hirotaka KosakaDepartment of Psychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.ORCID 0000-0003-2210-5025
Hidehiko OkazawaBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.ORCID 0000-0001-7046-3383
Yuichi KimuraFaculty of Informatics, Cyber Informatics Research Institute, Kindai University, Higashi-Osaka, Japan.
Masaru MimuraDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Takuya TakahashiDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan. takahast@yokohama-cu.ac.jp.ORCID 0000-0001-6523-0622

Funding

Japan Agency for Medical Research and Development (AMED) JP18dm0207023, JP20dm0107124, JP22dm0207072
6 · The paper itself

Abstract

Synaptic phenotypes in living patients with psychiatric disorders are poorly characterized. Excitatory glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) is a fundamental component for neurotransmission. We recently developed a positron emission tomography (PET) tracer for AMPAR, [

Indexed as

Mental DisordersReceptors, AMPAAdultAutism Spectrum DisorderBipolar DisorderBrainCarbon RadioisotopesFemaleHumansMaleMiddle AgedPositron-Emission TomographySchizophreniaCarbon RadioisotopesReceptors, AMPA

Identifiers

PMID39406998
PMCPMC12014498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.