Evidence map›Paper›PMID 39406974›Full record

Observational studySurgical endoscopy2024

Impact of a novel-covered colonic stent in obstructive colon cancer.

Takahiro Hiratsuka, Tomonori Akagi, Hidefumi Shiroshita, Akio Shiromizu, Shota Amano, Yoko Kawano, Yohei Kono, Shigeo Ninomiya, Tomotaka Shibara, Yoshitake Ueda and 5 more

Abstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Takahiro HiratsukaDepartment of Comprehensive Surgery for Community Medicine, Faculty of Medicine, Oita University, Oita, Japan. htakahiru@oita-u.ac.jp.ORCID 0000-0002-6483-6013
Tomonori AkagiDepartment of Comprehensive Surgery for Community Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Hidefumi ShiroshitaDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Akio ShiromizuDepartment of Surgery, Arita Gastrointestinal Hospital, Oita, Japan.
Shota AmanoDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Yoko KawanoDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Yohei KonoDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Shigeo NinomiyaDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Tomotaka ShibaraDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Yoshitake UedaDepartment of Comprehensive Surgery for Community Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Yorinobu SumidaDepartment of Gastroenterology, Kitakyusyu Municipal Medical Center, Fukuoka, Japan.
Shuji SaitoDivision of Surgery, Gastrointestinal Center, Yokohama Shin-Midori General Hospital, Kanagawa, Japan.
Tsuyoshi EtohDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Tsutomu DaDepartment of Diagnostic Pathology, Faculty of Medicine, Oita University, Oita, Japan.
Masafumi InomataDepartment of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.

Funding

SB-KAWASUMI LABORATORIES(Japan) D219F01023
6 · The paper itself

Abstract

backgroundAlthough the short-term outcomes of bridge-to-surgery (BTS) procedures using self-expandable metal stents are favorable, concerns remain regarding worsened prognosis due to tissue injury in the tumor area. Herein, we describe a newly developed covered stent, the Kawasumi Jabara colonic stent™, designed to reduce tissue damage/injury associated with stent-related complications in BTS procedures. This study aimed to evaluate the efficacy and safety of the Kawasumi Jabara colonic stent as a BTS for obstructive colorectal cancer (OCC).

methodsThis multicenter retrospective observational study included 44 OCC patients who underwent BTS with stents at four facilities between September 2020 and November 2022. The groups of patients receiving the Kawasumi Jabara and non-covered colonic stents were designated Groups C and NC, respectively. Treatment outcomes related to stent placement and surgery were compared using propensity score matching (PSM) analysis.

resultsGroups NC and C (n = 34 and 10, respectively) showed no significant differences in sex, age, tumor location, histological type, Colorectal Obstruction Scoring System (CROSS) score, or cStage; however, the stent placement duration was shorter in Group C. No significant differences were found in terms of the technical and clinical success rates for stent placement. Stent dislocation was observed in 0 and 2 cases in Groups C and NC, respectively. PSM analysis between eight cases, each from Groups C and NC, revealed no significant differences in stent-related or surgical outcomes between the groups. However, regarding the gross injury score in the resected specimens, Group C had a lower score than Group NC (1.8 vs. 5.5), and the proportion of pathological tissue injury involving deeper layers was also lower in Group C (37.5% vs. 100%).

conclusionsCompared to conventional non-covered stents, the Kawasumi Jabara colonic stent™ demonstrated favorable safety during stent insertion, retention, and surgery, with only mild tissue injury.

Indexed as

Colonic NeoplasmsIntestinal ObstructionStentsAgedAged, 80 and overFemaleHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesSelf Expandable Metallic StentsTreatment OutcomeColonic obstructionColorectal cancerCovered stent

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.