Evidence map›Paper›PMID 39406936›Full record

ArticleEJNMMI research2024

Appearance time of blood in the brain as a possible indicator of oxygen extraction fraction: a feasibility study.

Mitsumasa Murao, Nobuyuki Kudomi, Katsuya Mitamura, Takashi Norikane, Yuri Manabe, Yukito Maeda, Yuka Yamamoto, Tetsuhiro Hatakeyama, Yoshihiro Nishiyama

Abstract read
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In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mitsumasa MuraoDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Nobuyuki KudomiDepartment of Medical Physics, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Katsuya MitamuraDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Takashi NorikaneDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Yuri ManabeDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Yukito MaedaDepartment of Clinical Radiology, Kagawa University Hospital, Kagawa, Japan.
Yuka YamamotoDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan. yamamoto.yuka@kagawa-u.ac.jp.ORCID http://orcid.org/0000-0002-3912-4217
Tetsuhiro HatakeyamaDepartment of Neurological Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Yoshihiro NishiyamaDepartment of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.

Funding

Japan Society for the Promotion of Science 19K17201
6 · The paper itself

Abstract

backgroundImaging examination of cerebral blood flow (CBF), oxygen extraction fraction (OEF), and metabolic rate of oxygen is crucial for understanding the normal functioning and pathophysiology of the brain. A recently developed method estimates the appearance time of cerebral blood (ATB) pixel-wise from the imaging examination of CBF alone. In this study, we aimed to test the potential of ATB as an indicator of OEF.

resultsWe retrospectively reviewed patients (n = 62) with suspected cerebrovascular disorders including steno-occlusive disease who underwent positron emission tomography (PET) with

conclusionOur results indicate the potential of ATB as an indicator of OEF.

Indexed as

15O-labelled tracerAppearance time of bloodCerebral blood flowOxygen extraction fractionPositron emission tomography

Identifiers

PMID39406936
PMCPMC11480264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.