Evidence map›Paper›PMID 39406910›Full record

ReviewResults and problems in cell differentiation2024

Macrophage Polarization and Its Impact on Osteoporosis.

Junwei Yan, Chenyu Huang, Dongdong Jiang, Yan Xu, Zhuoli Zhang, Liming Wang, Bin Liang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Results and problems in cell differentiation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junwei Yan *Department of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Chenyu Huang *Department of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Dongdong JiangDepartment of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yan XuDepartment of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Zhuoli ZhangDepartment of Biomedical Engineering, University of California, Irvine, CA, USA.
Liming WangDepartment of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Bin LiangDepartment of Orthopedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to its reduced bone density and higher risk for fractures, osteoporosis remains an international public health crisis. Research highlights the essential role played by macrophage polarization in osteoporosis and indicates that the balance between pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages influences bone metabolism. This review examines how M1 and M2 macrophages contribute to the development of osteoporosis and evaluates existing therapeutic approaches aimed at controlling macrophage polarization. It also describes future study areas that will allow improved management and treatment of osteoporosis.

Indexed as

MacrophagesOsteoporosisAnimalsHumansHomeostasisMacrophageOsteoporosisPolarization

Identifiers

PMID39406910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.