Evidence map›Paper›PMID 39406523›Full record

ArticleBriefings in bioinformatics2024

MultiFeatVotPIP: a voting-based ensemble learning framework for predicting proinflammatory peptides.

Chaorui Yan, Aoyun Geng, Zhuoyu Pan, Zilong Zhang, Feifei Cui

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaorui YanSchool of Computer Science and Technology, Hainan University, 58 Renmin Avenue, Meilan District, Haidian Campus, Haikou 570228, China.
Aoyun GengSchool of Computer Science and Technology, Hainan University, 58 Renmin Avenue, Meilan District, Haidian Campus, Haikou 570228, China.
Zhuoyu PanInternational Business School, Hainan University, 58 Renmin Avenue, Meilan District, Haidian Campus, Haikou 570228, China.
Zilong ZhangSchool of Computer Science and Technology, Hainan University, 58 Renmin Avenue, Meilan District, Haidian Campus, Haikou 570228, China.
Feifei CuiSchool of Computer Science and Technology, Hainan University, 58 Renmin Avenue, Meilan District, Haidian Campus, Haikou 570228, China.ORCID 0000-0001-7055-3813

Funding

National Natural Science Foundation of China 62101100
6 · The paper itself

Abstract

Inflammatory responses may lead to tissue or organ damage, and proinflammatory peptides (PIPs) are signaling peptides that can induce such responses. Many diseases have been redefined as inflammatory diseases. To identify PIPs more efficiently, we expanded the dataset and designed an ensemble learning model with manually encoded features. Specifically, we adopted a more comprehensive feature encoding method and considered the actual impact of certain features to filter them. Identification and prediction of PIPs were performed using an ensemble learning model based on five different classifiers. The results show that the model's sensitivity, specificity, accuracy, and Matthews correlation coefficient are all higher than those of the state-of-the-art models. We named this model MultiFeatVotPIP, and both the model and the data can be accessed publicly at https://github.com/ChaoruiYan019/MultiFeatVotPIP. Additionally, we have developed a user-friendly web interface for users, which can be accessed at http://www.bioai-lab.com/MultiFeatVotPIP.

Indexed as

Machine LearningPeptidesAlgorithmsComputational BiologyHumansInflammationSoftwareVotingPeptidesensemble learningfeature encodinginflammationmachine learningproinflammatory peptide

Identifiers

PMID39406523
PMCPMC11479713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.