Evidence map›Paper›PMID 39405663›Full record

Trial reportSocial science & medicine (1982)2024

Mlambe economic and relationship-strengthening intervention for alcohol use decreases violence and improves relationship quality in couples living with HIV in Malawi.

Amy A Conroy, Allison Ruark, Nancy Mulauzi, James Mkandawire, Lynae A Darbes, Judith A Hahn, Torsten B Neilands, Scott Tebbetts, Fred M Ssewamala

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Social science & medicine (1982), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amy A ConroyDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA. Electronic address: amy.conroy@ucsf.edu.
Allison RuarkHealth Professions, Wheaton College, Wheaton, IL, USA.
Nancy MulauziInvest in Knowledge, Zomba, Malawi.
James MkandawireInvest in Knowledge, Zomba, Malawi.
Lynae A DarbesDepartment of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, USA.
Judith A HahnDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Torsten B NeilandsDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Scott TebbettsDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Fred M SsewamalaWashington University, Brown School, St. Louis, MO, USA.

Funding

Training in Research Program on Alcohol Use by Persons with our at Risk for HIVK24AA022586 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2013 to 2023
$1.8M
An economic and relationship-strengthening intervention for HIV-affected couples who drink alcohol in Malawi - Administrative SupplementR34AA027983 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2019 to 2022
$784k
NIAAA NIH HHS K24 AA022586NIAAA NIH HHS R34 AA027983
6 · The paper itself

Abstract

introductionA syndemic of unhealthy alcohol use, intimate partner violence (IPV), and economic insecurity threatens to derail progress towards UNAIDS 95-95-95 targets in sub-Saharan Africa. We developed a combined economic and relationship-strengthening intervention called Mlambe to reduce unhealthy alcohol use and increase adherence to antiretroviral therapy for couples in Malawi. This study evaluates the additional impact of Mlambe on IPV and relationship dynamics.

methodsIn a pilot randomized controlled trial, 78 married couples (156 individuals) living with HIV and reporting unhealthy alcohol use based on the AUDIT-C (at least one partner) were recruited from HIV care clinics in Zomba, Malawi. The intervention arm (39 couples) received a 10-month program consisting of incentivized savings accounts with financial literacy education, relationship education, and couples counseling sessions to build relationship skills. The control arm (39 couples) received enhanced usual care (EUC) with brief alcohol counseling. We used linear mixed-effects models to assess the effects of Mlambe on relationship quality (e.g., constructive communication, unity, sexual satisfaction) and IPV (physical, sexual, and emotional) by including fixed effects for treatment arm and a random effect for dyad, and tested whether effects on IPV and relationship quality differed by gender.

resultsAt 10- and 15-month follow-up visits, couples in the Mlambe arm showed greater increases in couple communication, unity, sexual satisfaction, intimacy, and trust (Cohen's d ranged from 0.36 to 0.56; p < 0.05) as compared to EUC. Couples in the Mlambe arm also showed significant decreases in physical and emotional IPV (Cohen's d ranged from 0.33 to 0.49; p < 0.05) as compared to EUC. Subsequent moderation analyses indicated that women reported significantly greater improvements in relationship quality than men, except for sexual satisfaction (p < 0.05), and greater declines in physical IPV than men (p < 0.05).

conclusionsMlambe resulted in significant improvements in relationship quality and decreased IPV in couples, particularly for women who as a group reported lower relationship quality at baseline. Economic and relationship-strengthening interventions have potential to disrupt harmful syndemics of violence, substance use, and poverty among couples living with HIV. CLINICAL TRIAL NUMBER: NCT#04906616.

Indexed as

HIV InfectionsIntimate Partner ViolenceAdultAlcohol DrinkingAlcoholismFemaleHumansInterpersonal RelationsMalawiMaleMiddle AgedPilot ProjectsAlcohol useAntiretroviral therapyCouplesEconomic-strengtheningHIV/AIDSSub-saharan Africa

Identifiers

PMID39405663
PMCPMC11585424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.