Evidence map›Paper›PMID 39405500›Full record

ArticleRetinal cases & brief reports2025

PROGRESSIVE MACULOPATHY IN A CHILD RESULTING FROM VITREOPAPILLARY TRACTION ON A CONGENITALLY ANOMALOUS NERVE.

Ross M Kennamer-Chapman, Lee M Jampol, Rithwick Rajagopal

Abstract readCase Reports
In one paragraph

Article in Retinal cases & brief reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ross M Kennamer-ChapmanJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri; and.
Lee M JampolDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Rithwick RajagopalJohn F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri; and.ORCID 0000-0002-3036-2665

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Andrew Ruzycki · 1985 to 2026
$18.4M
Modulating retinal lipid biogenesis in diabetes for therapeutic effectsR01EY034172 · NEI · WASHINGTON UNIVERSITY · PI Rithwick Rajagopal · 2022 to 2026
$1.9M
Horncrest Foundation Unrestricted AwardNEI NIH HHS EY034172NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY034172
6 · The paper itself

Abstract

purposeTo present a case of worsening maculopathy and vision loss because of vitreopapillary traction associated with an anomalous optic nerve head in a pediatric patient successfully managed with pars plana vitrectomy.

methodsRetrospective case report.

resultsA 13-year-old boy presented with unilateral maculopathy that slowly progressed over a 4-year period. As his visual acuity declined, he became increasingly symptomatic. The macular pathology occurred in the setting of vitreopapillary traction overlying multiple congenital optic nerve abnormalities, including a myelinated nerve fiber layer and a Bergmeister papilla. After pars plana vitrectomy to alleviate the traction, the patient's macular appearance improved, and his vision slowly recovered to baseline.

conclusionThere are limited reports of congenital optic nerve anomalies associated with vitreopapillary traction and maculopathy among any age group. This report illustrates a pediatric case in which removal of traction on the nerve head by pars plana vitrectomy was the key therapeutic intervention to alleviate the maculopathy.

Indexed as

Optic DiskOptic NerveRetinal DiseasesVitreous BodyAdolescentDisease ProgressionHumansMaleRetrospective StudiesVisual AcuityVitrectomyBergmeister papillamaculopathymyelinated nerve fiber layervitrectomy

Identifiers

PMID39405500
PMCPMC12570612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.