Evidence map›Paper›PMID 39405479›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

MrgprC11

Yanyan Xing, Yeseul Nho, Katy Lawson, Yuyan Zhu, Alexandra E Ellison, Margaret Y Chang, William Hancock, Liang Han

Abstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. VipCell reports · 2026
    Article
  2. Basophils activate oncostatin M receptor-expressing vagal sensory neurons.The Journal of allergy and clinical immunology · 2026
    Article
  3. Molecular, anatomical, and functional organization of lung interoceptors.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Cracking the Code of the Jugular Vagal Sensory Neurons in Allergic Airway Responsiveness.American journal of respiratory cell and molecular biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Yanyan XingSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0002-8431-9902
Yeseul NhoSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0009-0009-9178-8924
Katy LawsonSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0002-9364-2410
Yuyan ZhuSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0002-2928-6167
Alexandra E EllisonSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0009-0003-4453-2842
Margaret Y ChangSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0009-0006-7791-3491
William HancockSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0009-0004-0666-5879
Liang HanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0001-8674-6433

Funding

The function of MrgprC11+ vagal sensory neurons in the airwayR01HL141269 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAN, LIANG · 2018 to 2022
$1.9M
Interoceptors controlling airway constrictionR01HL173002 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI Liang Han · 2024 to 2026
$1.4M
Division of Integrative Organismal Systems 2334697NHLBI NIH HHS R01 HL141269NHLBI NIH HHS R01 HL173002NIH HHS HL141269
6 · The paper itself

Abstract

The lung is densely innervated by sensory nerves, the majority of which are derived from the vagal sensory neurons. Vagal ganglia consist of two different ganglia, termed

Indexed as

AsthmaInflammationRespiratory HypersensitivitySensory Receptor CellsAnimalsBronchoconstrictionDisease Models, AnimalInterleukin-4LungMiceMice, Inbred C57BLNodose GanglionInterleukin-4airway hyperresponsivenessallergic asthmajugular neuronsneuroimmune interactionsvagal sensory neurons

Identifiers

PMID39405479
PMCPMC12005045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.