Evidence map›Paper›PMID 39405097›Full record

ArticleeLife2024

Heat Shock Factor 1 forms nuclear condensates and restructures the yeast genome before activating target genes.

Linda S Rubio, Suman Mohajan, David S Gross

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026
    Review
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  6. Deciphering the role ofMicrobiology spectrum · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Linda S RubioDepartment of Biochemistry and Molecular Biology Louisiana State University Health Sciences Center, Shreveport, United States.ORCID https://orcid.org/0000-0002-7260-6971
Suman MohajanDepartment of Biochemistry and Molecular Biology Louisiana State University Health Sciences Center, Shreveport, United States.ORCID https://orcid.org/0000-0002-8913-9425
David S GrossDepartment of Biochemistry and Molecular Biology Louisiana State University Health Sciences Center, Shreveport, United States.ORCID https://orcid.org/0000-0002-7957-8790

Funding

Genome Architecture and Gene Control in Response to StressR01GM138988 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI GROSS, DAVID SAMUEL · 2020 to 2023
$1.2M
Role of Actin in the Chromosomal Conformation & Nuclear Organization of HSP GenesR15GM128065 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI GROSS, DAVID SAMUEL · 2018 to 2019
$523k
NIGMS NIH HHS R01 GM138988NIGMS NIH HHS R15 GM128065NIH HHS R01 GM138988NIH HHS R15 GM128065
6 · The paper itself

Abstract

In insects and mammals, 3D genome topology has been linked to transcriptional states yet whether this link holds for other eukaryotes is unclear. Using both ligation proximity and fluorescence microscopy assays, we show that in

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA-Binding ProteinsEthanolGene Expression Regulation, FungalGenome, FungalHeat-Shock ProteinsHeat-Shock ResponseHeat Shock Transcription FactorsTranscription FactorsDNA-Binding ProteinsEthanolHeat-Shock ProteinsHeat Shock Transcription FactorsHSF1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factors3D genomechromatinchromosomesethanol stressgene expressionheat shock responseRNA Pol IIS. cerevisiaetranscriptional condensates

Identifiers

PMID39405097
PMCPMC11479590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.