Evidence map›Paper›PMID 39404969›Full record

ArticleDiscover oncology2024

Expression of CLDN1 and EGFR in PTC.

JunJie Wu, YouMei Wang, Lei Yan, YaWen Dong

Abstract read
In one paragraph

Article in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Identification and assessment ofOncology letters · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

JunJie WuDepartment of Pathology, the First People's Hospital of Pinghu, Jiaxing, Zhejiang, People's Republic of China.
YouMei WangDepartment of Pathology, the First People's Hospital of Pinghu, Jiaxing, Zhejiang, People's Republic of China.
Lei YanDepartment of Pathology, the First People's Hospital of Pinghu, Jiaxing, Zhejiang, People's Republic of China.
YaWen DongDepartment of Pathology, the First People's Hospital of Pinghu, Jiaxing, Zhejiang, People's Republic of China. 15824332645@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary thyroid carcinoma (PTC) involves complex genetic mechanisms, notably involving CLDN1 and EGFR. This study investigates the expression and variations of these genes and their effects on tumor behavior and patient outcomes. Meta-analysis of CLDN1 and EGFR expression in TCGA-PTC patients and GEO datasets was conducted. cBioPortal was used for clinical analysis. GSEA, GO, KEGG, Hallmark pathways, and cibersort analysis were applied. Cell proliferation, migration, invasion, and apoptosis were assessed in vitro. Co-culturing with CD8

Indexed as

CLDN1EGFREpithelial–mesenchymal transitionMeta-analysisPapillary thyroid carcinoma

Identifiers

PMID39404969
PMCPMC11480332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.