Evidence map›Paper›PMID 39404881›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Comparative analysis of classic and delayed Ménière's disease: clinical characteristics and endolymphatic hydrops manifestations in an Asian cohort.

Suming Shi, Xu Liu, Wenquan Li, Dan Wang, Wuqing Wang

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Suming Shi *ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Fenyang Road No.83, Shanghai, 200031, China.
Xu Liu *ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Fenyang Road No.83, Shanghai, 200031, China.
Wenquan Li *Department of Otolaryngology, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Dan WangENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Fenyang Road No.83, Shanghai, 200031, China.
Wuqing WangENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Fenyang Road No.83, Shanghai, 200031, China. wwuqing@eent.shmu.edu.cn.ORCID http://orcid.org/0000-0002-7395-9525

Funding

the National Natural Science Foundation of China 82101222
6 · The paper itself

Abstract

objectiveTo investigate the clinical characteristics and endolymphatic hydrops (ELH) Manifestations in patients with delayed Ménière's disease (DMD) compared to classic Ménière's disease (CMD).

methodsA prospective cohort study was conducted involving 523 patients diagnosed with MD. Clinical data, inner ear function, and ELH characteristics were analyzed and compared between CMD and DMD groups. Assessments included audiometry, VEMP, and MRI.

resultsDMD prevalence was 6.1%. Bilateral MD was significantly more common in DMD (34.4% vs. 14.5%, P = 0.003). DMD patients had more severe hearing loss in the first involved ear and more deteriorated VEMP in the contralateral ear (P < 0.05). ELH was present in 100% of affected ears, with a higher contralateral ELH proportion in DMD (34.4% vs. 15.0%, P = 0.005).

conclusionsDMD patients exhibit a higher prevalence of bilateral MD, more severe hearing loss, and greater contralateral ELH compared to CMD patients. Both subtypes share similar ELH characteristics, suggesting common underlying mechanisms.

Indexed as

Endolymphatic HydropsMeniere DiseaseAdultAgedAudiometryAudiometry, Pure-ToneFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrevalenceProspective StudiesVestibular Evoked Myogenic PotentialsBilateral ménière’s diseaseClassic ménière’s diseaseClinical characteristicsDelayed ménière’s diseaseEndolymphatic hydrops

Identifiers

PMID39404881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.