Evidence map›Paper›PMID 39404879›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Seasonal variation and demographic characteristics of acute tonsillitis and peritonsillar abscess in ENT practices in Germany (2019-2023).

David Ulrich Seidel, Simon Bode, Karel Kostev

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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5 · Who and what money

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3 authors.

David Ulrich SeidelDepartment of Otorhinolaryngology, Facial Plastic Surgery, Gummersbach District Hospital, Gummersbach, Germany.
Simon BodeDepartment of Otorhinolaryngology, Facial Plastic Surgery, Gummersbach District Hospital, Gummersbach, Germany.
Karel KostevEpidemiology IQVIA, Darmstädter Landstraße 108, 60598, Frankfurt am Main, Germany. Karel.Kostev@iqvia.com.ORCID http://orcid.org/0000-0002-2124-7227

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePeritonsillar abscess (PTA) is a common soft tissue infection of the head and neck. It remains unclear to what extent inflammatory diseases of the palatine tonsils or other infections contribute to the development of PTA. This study examines the demographic characteristics and seasonal variations of acute tonsillitis (aT) and PTA in ENT practices in Germany using a practice database.

methodsRetrospective analysis based on data from the German-wide IQVIA

results59,934 cases of aT and 5,024 cases of PTA were recorded. The mean age was 30.3 years (aT) and 39.4 years (PTA). The proportion of female patients was 60% (aT) and 49% (PTA). Both diagnoses showed seasonal variations with peaks in winter and spring and a decline in summer, although the decline was less pronounced for PTA. The monthly case numbers of aT and PTA showed high correlations between r = 0.75 (2019) and r = 0.94 (2020). The average correlation for the period 2019-2023 was r = 0.81. During the coronavirus pandemic, a significant decrease in the case numbers of both diseases was observed, while the typical seasonal variations disappeared. After the pandemic, the case numbers increased to higher levels than before the pandemic.

conclusionsaT and PTA both show seasonal variations with peaks in winter and spring and a decline in summer. The correlation between the variations of aT and PTA could be related to a partly common aetiology or to the specific sample of the practice database. The attenuation of seasonal variation during the coronavirus pandemic illustrates the impact of COVID-19 on the incidence of other diseases and on the use of healthcare pathways by patients.

Indexed as

Peritonsillar AbscessSeasonsTonsillitisAcute DiseaseAdolescentAdultAgedChildChild, PreschoolCOVID-19FemaleGermanyHumansInfantMaleMiddle AgedAcute tonsillitisCOVID-19 pandemicENT practicesGermanyPeritonsillar abscessPractice databaseSeasonal variation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.