Evidence map›Paper›PMID 39404823›Full record

ArticleThe Journal of cell biology2024

Making lipids very unhappy to discover how they bind to proteins.

Christopher Stefan, Roberto Covino

Abstract read
In one paragraph

Article in The Journal of cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher StefanLaboratory for Molecular Cell Biology, University College London, London, UK.ORCID 0000-0002-4118-5721
Roberto CovinoInstitute of Computer Science, Goethe University Frankfurt, and Frankfurt Institute for Advanced Studies , Frankfurt, Germany.ORCID 0000-0003-0884-0402

Funding

Frankfurt Institute for Advanced StudiesGoethe University FrankfurtUK Research and Innovation Biotechnology and Biological Sciences Research Council BB/X017184/1
6 · The paper itself

Abstract

Membrane lipid composition is maintained by conserved lipid transfer proteins, but computational approaches to study their lipid-binding mechanisms are limiting. Srinivasan et al. (https://doi.org/10.1083/jcb.202312055) develop a clever molecular dynamics simulations assay to accurately model lipid-binding poses in lipid transfer proteins.

Indexed as

Molecular Dynamics SimulationProtein BindingCarrier ProteinsHumansLipidsMembrane LipidsCarrier ProteinsLipidslipid transfer proteinMembrane Lipids

Identifiers

PMID39404823
PMCPMC11486829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.