Evidence map›Paper›PMID 39404767›Full record

ArticleBioinformatics (Oxford, England)2024

SurvBal: compositional microbiome balances for survival outcomes.

Ying Li, Teresa Lee, Kai Marin, Xing Hua, Sujatha Srinivasan, David N Fredricks, John R Lee, Wodan Ling

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying LiDivision of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY 10065, United States.ORCID 0000-0001-5429-0080
Teresa LeePublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.
Kai MarinPublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.
Xing HuaPublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.
Sujatha SrinivasanVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.ORCID 0000-0002-7267-3859
David N FredricksVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.
John R LeeDivision of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, United States.
Wodan LingDivision of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY 10065, United States.ORCID 0000-0001-7196-8543

Funding

Joint Analysis of Microbiome and Other Genomic Data TypesR01GM129512 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI WU, MICHAEL CHIAO-AN · 2018 to 2021
$1.6M
Robust Statistical Methods for Longitudinal Microbiome StudiesR01GM155734 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Wodan Ling · 2024 to 2026
$1.2M
NIGMS NIH HHS R01 GM129512NIGMS NIH HHS R01 GM155734
6 · The paper itself

Abstract

summaryIdentification of balances of bacterial taxa in relation to continuous and dichotomous outcomes is an increasingly frequent analytic objective in microbiome profiling experiments. SurvBal enables the selection of balances in relation to censored survival or time-to-event outcomes which are of considerable interest in many biomedical studies. The most commonly used survival models-the Cox proportional hazards and parametric survival models are included in the package, which are used in combination with step-wise selection procedures to identify the optimal associated balance of microbiome, i.e. the ratio of the geometric means of two groups of taxa's relative abundances. AVAILABILITY AND IMPLEMENTATION: The SurvBal R package and Shiny app can be accessed at https://github.com/yinglia/SurvBal and https://yinglistats.shinyapps.io/shinyapp-survbal/.

Indexed as

MicrobiotaSoftwareBacteriaHumansProportional Hazards ModelsSurvival Analysis

Identifiers

PMID39404767
PMCPMC11639162

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.