Evidence map›Paper›PMID 39404642›Full record

ArticleACS applied materials & interfaces2024

Cytocompatible Hydrogels with Tunable Mechanical Strength and Adjustable Swelling Properties through Photo-Cross-Linking of Poly(vinylphosphonates).

Anton S Maier, Salma Mansi, Kerstin Halama, Philipp Weingarten, Petra Mela, Bernhard Rieger

Abstract read
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Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anton S MaierTechnical University of Munich, Germany, TUM School of Natural Sciences, Department of Chemistry, WACKER-Chair of Macromolecular Chemistry, Lichtenbergstraße 4, 85748 Garching, Germany.
Salma MansiTechnical University of Munich, Germany, TUM School of Engineering and Design, Department of Mechanical Engineering, Chair of Medical Materials and Implants, Munich Institute of Biomedical Engineering, Munich Institute of Integrated Materials, Energy and Process Engineering, Boltzmannstraße 15, 85748 Garching, Germany.ORCID 0000-0001-5052-9840
Kerstin HalamaTechnical University of Munich, Germany, TUM School of Natural Sciences, Department of Chemistry, WACKER-Chair of Macromolecular Chemistry, Lichtenbergstraße 4, 85748 Garching, Germany.
Philipp WeingartenTechnical University of Munich, Germany, TUM School of Natural Sciences, Department of Chemistry, WACKER-Chair of Macromolecular Chemistry, Lichtenbergstraße 4, 85748 Garching, Germany.
Petra MelaTechnical University of Munich, Germany, TUM School of Engineering and Design, Department of Mechanical Engineering, Chair of Medical Materials and Implants, Munich Institute of Biomedical Engineering, Munich Institute of Integrated Materials, Energy and Process Engineering, Boltzmannstraße 15, 85748 Garching, Germany.ORCID 0000-0001-6503-076X
Bernhard RiegerTechnical University of Munich, Germany, TUM School of Natural Sciences, Department of Chemistry, WACKER-Chair of Macromolecular Chemistry, Lichtenbergstraße 4, 85748 Garching, Germany.ORCID 0000-0002-0023-884X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, the synthesis, characterization, and application of a novel synthetic hydrogel based on the photoinitiated cross-linking of poly(vinylphosphonates) is presented. First, statistical copolymers with adjustable ratios of the monomers diallyl vinylphosphonate (DAlVP) and diethyl vinylphosphonate (DEVP), as well as different molecular weights, were obtained via rare earth metal-mediated group-transfer polymerization (REM-GTP) while maintaining narrow polydispersities. The copolymers were cross-linked by applying photoinitiated thiol-ene click chemistry (λ = 365 nm). The network formation was monitored via oscillatory rheology coupled with UV-irradiation, revealing the high spatiotemporal control of the reaction. Moreover, the equilibrium storage moduli of poly(vinylphosphonate)-based hydrogels increased with a growing number of DAlVP units and upon application of a different cross-linker, which was additionally confirmed by nanoindentation experiments. In contrast, the water uptake of hydrogels decreased with higher DAlVP amounts in the corresponding hydrogels due to lower chain mobility and an overall increase in the hydrophobicity of the samples. Upon successful functionalization of P(DEVP-

Indexed as

HydrogelsOrganophosphonatesAnimalsAnti-Bacterial AgentsBiocompatible MaterialsCross-Linking ReagentsEscherichia coliHumansMicePolymersAnti-Bacterial AgentsBiocompatible MaterialsCross-Linking ReagentsHydrogelsOrganophosphonatesPolymerscatalytic polymerizationcytocompatibilityhydrogeloscillatory rheologythiol−ene click reaction

Identifiers

PMID39404642
PMCPMC11533175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.