Evidence map›Paper›PMID 39404420›Full record

ArticleCells2024

Adenosine Metabolism Pathway Alterations in Frontal Cortical Neurons in Schizophrenia.

Smita Sahay, Emily A Devine, Christina F-A Vargas, Robert E McCullumsmith, Sinead M O'Donovan

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Smita SahayDepartment of Neurosciences & Psychiatry, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0009-0003-4377-8963
Emily A DevineDepartment of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.ORCID 0009-0002-2631-9506
Christina F-A VargasDepartment of Neurosciences & Psychiatry, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0009-0008-0336-1422
Robert E McCullumsmithDepartment of Neurosciences & Psychiatry, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0000-0001-6921-7150
Sinead M O'DonovanDepartment of Neurosciences & Psychiatry, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0000-0003-3172-4952

Funding

Cell-specific analysis of sub-kinomes in schizophreniaR01MH107487 · NIMH · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI MCCULLUMSMITH, ROBERT E, MELLER, JAREK · 2016 to 2020
$1.9M
American Foundation of Suicide Prevention YIG-1-139-20NIMH NIH HHS MH107487
6 · The paper itself

Abstract

Schizophrenia is a neuropsychiatric illness characterized by altered neurotransmission, in which adenosine, a modulator of glutamate and dopamine, plays a critical role that is relatively unexplored in the human brain. In the present study, postmortem human brain tissue from the anterior cingulate cortex (ACC) of individuals with schizophrenia (

Indexed as

AdenosineAdenosine KinaseNeuronsSchizophrenia5'-NucleotidaseAdultAgedApyraseCase-Control StudiesEquilibrative Nucleoside Transporter 1FemaleFrontal LobeGPI-Linked ProteinsHumansMaleMiddle Aged5'-NucleotidaseAdenosineAdenosine KinaseApyraseEquilibrative Nucleoside Transporter 1GPI-Linked ProteinsNT5E protein, humanRNA, Messengeradenosine kinaseanterior cingulate cortexecto-5′-nucleotidasesectonucleoside triphosphate diphosphohydrolasesequilibrative nucleoside transportersneuromodulationpyramidal neuronsschizophrenia

Identifiers

PMID39404420
PMCPMC11475131

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.