Evidence map›Paper›PMID 39404372›Full record

ArticleCells2024

Treadmill Exercise Facilitates Synaptic Plasticity in

Laikang Yu, Yan Li, Yuanyuan Lv, Boya Gu, Jiajia Cai, Qing-Song Liu, Li Zhao

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laikang YuDepartment of Strength and Conditioning Assessment and Monitoring, Beijing Sport University, Beijing 100084, China.ORCID 0000-0001-7649-5095
Yan LiBeijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.
Yuanyuan LvBeijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.
Boya GuBeijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.
Jiajia CaiBeijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.
Qing-Song LiuDepartment of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0003-1858-1504
Li ZhaoBeijing Key Laboratory of Sports Performance and Skill Assessment, Beijing Sport University, Beijing 100084, China.ORCID 0000-0001-7049-880X

Funding

Chinese Universities Scientific Fund 2021QN001National Key Research and Development Program of China 2022YFC3600201National Natural Science Foundation of China 31571229
6 · The paper itself

Abstract

Accumulating evidence underscores exercise as a straightforward and cost-effective lifestyle intervention capable of mitigating the risk and slowing the emergence and progression of Alzheimer's disease (AD). However, the intricate cellular and molecular mechanisms mediating these exercise-induced benefits in AD remain elusive. The present study delved into the impact of treadmill exercise on memory retrieval performance, hippocampal synaptic plasticity, synaptic morphology, and the expression and activity of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic receptors (AMPARs) in 6-month-old

Indexed as

HippocampusMice, Inbred C57BLMice, TransgenicNeuronal PlasticityPhysical Conditioning, AnimalAlzheimer DiseaseAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalLong-Term PotentiationMaleMemoryMicePresenilin-1Receptors, AMPASynapsesAmyloid beta-Protein PrecursorPresenilin-1Receptors, AMPAAlzheimer’s diseaseAMPA receptorexercisesynaptic plasticity

Identifiers

PMID39404372
PMCPMC11475322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.