ArticleDevelopmental medicine and child neurology2025
Cerebral palsy characteristics in term-born children with and without detectable perinatal risk factors: A cross-sectional study.
Article in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Characteristics of unilateral cerebral palsy according to gestational age at birth: A retrospective study.Developmental medicine and child neurology · 2026Article
- Prediction tool for independent walking in children with dyskinetic cerebral palsy: a modeling study.BMC pediatrics · 2026Article
- Development of an evidence-based knowledge translation intervention to promote behavioral change in cerebral palsy diagnosis.Frontiers in public health · 2026Article
- Is it now possible to identify all newborn infants at risk of cerebral palsy?Developmental medicine and child neurology · 2025Article
- Cerebral palsy characteristics in term-born children with and without detectable perinatal risk factors: A cross-sectional study.Developmental medicine and child neurology · 2025Article
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8 authors.
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Abstract
aimTo compare, in term-born children with cerebral palsy (CP), the characteristics of those who exhibit detectable risk factors for CP at birth with those who do not.
methodThis was a cross-sectional study of term-born children using the Canadian Cerebral Palsy Registry comparing those with and without perinatal risk factors and/or neonatal symptoms for pregnancy, birth and neonatal characteristics, magnetic resonance imaging (MRI) findings, CP subtype, and impairment severity. Risk factors were quantified with a CP risk calculator. Multivariable and multinomial regressions were expressed as odds ratios (OR) and relative risk ratios.
resultsOf 1333 term-born children, 781 (58.6%) had complete variables for the CP risk calculator, of whom 195 (25%) had 'undetectable' newborn infant CP risk, and they did not have greater postneonatal brain injury. Focal injury on MRI was more common (OR 2.0, 95% confidence interval [CI] 1.3-3.1) than in the 'detectable' group. The 'undetectable' group had more unilateral CP (OR 1.8, 95% CI 1.3-2.6), less severe motor impairment (OR 0.76, 95% CI 0.67-0.86), and were more verbal (OR 2.3, 95% CI 1.5-3.6).
interpretationIn the Canadian CP Registry, one-quarter of term-born children lacked neonatal encephalopathy, seizures, or perinatal risk factors. They were more likely to have unilateral CP, focal MRI findings, and communicate with words than children with risk factors or neonatal symptoms.
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