Evidence map›Paper›PMID 39403951›Full record

ArticleEuropean heart journal. Acute cardiovascular care2024

Emergency department use of a high-sensitivity point-of-care troponin assay reduces length of stay: an implementation study preliminary report.

John W Pickering, Laura R Joyce, Christopher M Florkowski, Vanessa Buchan, Laura Hamill, Martin P Than

Abstract read
In one paragraph

Article in European heart journal. Acute cardiovascular care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Best of cardiovascular biomarkers.European heart journal. Acute cardiovascular care · 2025
    Article
  2. Article
  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John W PickeringDepartment of Medicine, University of Otago Christchurch, Christchurch, New Zealand.ORCID 0000-0001-9475-0344
Laura R JoyceDepartment of Surgery and Critical Care, University of Otago Christchurch, Christchurch, New Zealand.ORCID 0000-0001-8113-3814
Christopher M FlorkowskiCanterbury Health Laboratories, Christchurch Hospital, Christchurch, New Zealand.
Vanessa BuchanCanterbury Health Laboratories, Christchurch Hospital, Christchurch, New Zealand.
Laura Hamill24hr Surgery, Pegasus Health (Charitable), 401 Madras Street, Christchurch, New Zealand.ORCID 0000-0002-8829-9224
Martin P ThanDepartment of Medicine, University of Otago Christchurch, Christchurch, New Zealand.ORCID 0000-0001-9399-5227

Funding

Emergency Care FoundationNZ government Health Research Grant HRC 19-234
6 · The paper itself

Abstract

aimsPoint-of-care (POC) high-sensitivity troponin (hs-cTn) assays within a clinical pathway may safely reduce length of stay (LoS) for patients presenting to the emergency department (ED) with possible acute myocardial infarction (AMI). In this early report, we present the first evaluation of a POC hs-cTn in real-life care. METHODS AND

resultsIn adult patients presenting to ED investigated for possible AMI, we compared the LoS in patients assessed with a troponin in the 8 weeks before (usual-care phase) and the 8 weeks following introduction of the Siemens Atellica VTLi POC hs-cTnI for decision-making (intervention phase). The VTLi replaced the laboratory (Beckman Coulter) assay as the default hs-cTn test within the clinical pathway. This was the only change to the pathway process. The safety outcome was first event AMI or cardiac death within 30 days. There were 2376 presentations in the usual-care phase with 188 individuals with AMI and 2392 in the intervention phase with 198 AMI. In the intervention phase, there was a mean (95% CI) reduction in LoS of 32 min (22-41 min) compared with the usual-care phase. This represents 21.4 fewer patient-hours in the ED each day (1196 in the 8-week period). In both phases, the pathway correctly identified all cases of AMI at index attendance. There were four follow-up events (two usual-care, two intervention) within 30 days.

conclusionThe deployment of a hs-cTn POC analyser into a large ED safely reduced length of stay. If translatable to other EDs, this could represent an important advancement to patient care.

trial registrationAustralia New Zealand Clinical Trials Registry, No. ACTRN12619001189112.

Indexed as

BiomarkersEmergency Service, HospitalLength of StayMyocardial InfarctionPoint-of-Care SystemsAgedFemaleHumansMaleMiddle AgedTroponinBiomarkersTroponinAccelerated diagnostic pathwayAcute myocardial infarctionEmergency departmentEmergency roomHigh-sensitivity cardiac troponinPoint of care

Identifiers

PMID39403951
PMCPMC11666305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.