Evidence map›Paper›PMID 39403810›Full record

ArticleHypertension (Dallas, Tex. : 1979)2024

Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia.

Anne-Sophie van Wingerden, Maria Katsidoniotaki, Noora Haghighi, Casandra Almonte, Helen Woolcock Martinez, Eduard Valdes, Pedro Castro, Aymen Alian, Whitney Booker, Natalie A Bello and 4 more

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anne-Sophie van WingerdenDepartment of Obstetrics and Gynecology (A.-S.v.W., C.A., H.W.M., W.B.), Columbia University, New York, NY.ORCID 0009-0005-2759-9767
Maria KatsidoniotakiDepartment of Civil Engineering and Engineering Mechanics (M.K., I.A.K.), Columbia University, New York, NY.ORCID 0009-0002-0596-4629
Noora HaghighiDepartment of Neurology (N.H., E.V., R.S.M., E.C.M.), Columbia University, New York, NY.
Casandra AlmonteDepartment of Obstetrics and Gynecology (A.-S.v.W., C.A., H.W.M., W.B.), Columbia University, New York, NY.
Helen Woolcock MartinezDepartment of Obstetrics and Gynecology (A.-S.v.W., C.A., H.W.M., W.B.), Columbia University, New York, NY.ORCID 0009-0000-6640-1163
Eduard ValdesDepartment of Neurology (N.H., E.V., R.S.M., E.C.M.), Columbia University, New York, NY.ORCID 0000-0002-3532-9194
Pedro CastroDepartment of Neurology, Faculty of Medicine, São João Hospital Center, University of Porto, Portugal (P.C.).ORCID 0000-0003-1401-2398
Aymen AlianDivision of Obstetric and Gynecologic Anesthesiology, Department of Anesthesiology (A.A.), Yale University School of Medicine, New Haven, CT.ORCID 0000-0002-4810-8155
Whitney BookerDepartment of Obstetrics and Gynecology (A.-S.v.W., C.A., H.W.M., W.B.), Columbia University, New York, NY.ORCID 0000-0003-0405-069X
Natalie A BelloDepartment of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA (N.A.B.).ORCID 0000-0003-3257-3623
Randolph S MarshallDepartment of Neurology (N.H., E.V., R.S.M., E.C.M.), Columbia University, New York, NY.ORCID 0000-0003-3037-0283
Ioannis A KougioumtzoglouDepartment of Civil Engineering and Engineering Mechanics (M.K., I.A.K.), Columbia University, New York, NY.ORCID 0000-0002-2257-4203
Nils H PetersenDivision of Stroke and Neurocritical Care, Department of Neurology (N.H.P.), Yale University School of Medicine, New Haven, CT.ORCID 0000-0001-9711-3340
Eliza C MillerDepartment of Neurology (N.H., E.V., R.S.M., E.C.M.), Columbia University, New York, NY.ORCID 0000-0002-7108-8906

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Neurovascular Unit Dysfunction in Women with Severe PreeclampsiaK23NS107645 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2019 to 2023
$1.1M
Blood Pressure Measurement and Hypertension in PregnancyK23HL136853 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2018 to 2022
$948k
NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR001873NHLBI NIH HHS K23 HL136853NINDS NIH HHS K23 NS107645
6 · The paper itself

Abstract

backgroundPreeclampsia is associated with autonomic dysregulation during pregnancy; however, less is known about autonomic function in the first week postpartum after preeclampsia.

methodsWe retrospectively analyzed data from a prospective cohort of women with and without preeclampsia. Continuous blood pressure and heart rate were measured with finger plethysmography within 7 days postpartum. Frequency-domain blood pressure and heart rate variability (HRV) were calculated using spectral analysis. Time-domain HRV was calculated as the root mean square of successive R-R interval differences. We compared results between those with and without preeclampsia, as well as between those with new-onset preeclampsia, chronic hypertension with superimposed preeclampsia, and normotensive participants.

resultsA total of 70 postpartum women were enrolled: 20 normotensive, 29 new-onset preeclampsia, and 21 superimposed preeclampsia. Both low- and high-frequency blood pressure variabilities were higher in those with preeclampsia compared with controls (

conclusionsPostpartum patients with preeclampsia with and without chronic hypertension had lower HRV compared with normotensive postpartum controls. Higher blood pressure variability was observed only in those with nonsuperimposed preeclampsia, suggesting that the autonomic profile of preeclampsia may differ in patients with chronic hypertension.

Indexed as

Blood PressureHeart RatePostpartum PeriodPre-EclampsiaAdultAutonomic Nervous SystemBlood Pressure DeterminationFemaleHumansPregnancyProspective StudiesRetrospective Studiesblood pressurecardiovascular diseasesheart ratehypertensionpreeclampsiapregnancy

Identifiers

PMID39403810
PMCPMC11578794

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.