Evidence map›Paper›PMID 39403720›Full record

ArticleJournal of microbiology and biotechnology2024

Antimicrobial Activity of Cold Atmospheric Plasma on Bacterial Strains Derived from Patients with Diabetic Foot Ulcers.

Roopak Murali, Pooja Singh, Divya Ragunathan, Ramya Damarla, Dharshini Kichenaradjou, Kirtanna Malichetty Surriyanarayanan, Satish Kumar Jayaram, Harish C Chandramoorthy, Ashish Kumar, Mary Elizabeth Gnanambal Krishnan and 1 more

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roopak MuraliDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Pooja SinghDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Divya RagunathanDepartment of Biotechnology, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Ramya DamarlaDepartment of Biotechnology, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Dharshini KichenaradjouDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Kirtanna Malichetty SurriyanarayananDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Satish Kumar JayaramDepartment of Plastic Surgery, Sri Ramachandra Medical College, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Harish C ChandramoorthyDepartment of Microbiology & Clinical Parasitology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Ashish KumarDepartment of Microbiology & Clinical Parasitology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Mary Elizabeth Gnanambal KrishnanDepartment of Biotechnology, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.
Rajesh Kumar GandhirajanDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai 600116, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections or their biofilms in diabetic foot ulcer (DFU) are a key cause of drug-resistant wounds and amputations. Cold atmospheric plasma (CAP) is well documented for its antibacterial effect and promoting wound healing. In the current study, we built an argon-based, custom CAP device and investigated its potential in eliminating laboratory and clinical bacterial strains derived from DFU. The CAP device performed as expected with generation of hydroxyl, reactive nitrogen species, and argon species as determined by optical emission spectroscopy. A dose-dependent increase in oxidation reduction potential (ORP) and nitrites in the liquid phase was observed. The CAP treatment eliminated both gram-positive (

Indexed as

Anti-Bacterial AgentsBiofilmsDiabetic FootPlasma GasesBacteriaBacterial InfectionsDNA DamageGram-Positive BacteriaHumansMicrobial Sensitivity TestsPseudomonas aeruginosaReactive Nitrogen SpeciesStaphylococcus aureusAnti-Bacterial AgentsPlasma GasesReactive Nitrogen Speciesbacteriacold atmospheric plasmaDiabetic foot ulcernitric oxidereactive oxygen species

Identifiers

PMID39403720
PMCPMC11637820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.