Evidence map›Paper›PMID 39403378›Full record

ArticleFrontiers in immunology2024

Nonclinical evaluations of deucravacitinib and Janus kinase inhibitors in homeostatic and inflammatory pathways.

Brandon Johnson, Lihong Cheng, Jennifer Koenitzer, Ian M Catlett, Peter Schafer

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Pharmacologic Inhibition of JAK1/2 Potentiates Aminoglycoside-Induced Ototoxicity.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brandon JohnsonTranslational Medicine, Immunology, Cardiovascular & Neuroscience Disease Team, Bristol Myers Squibb, Princeton, NJ, United States.
Lihong ChengImmunology Thematic Research Centers (TRC), Bristol Myers Squibb, Princeton, NJ, United States.
Jennifer KoenitzerTranslational Medicine, Immunology, Cardiovascular & Neuroscience Disease Team, Bristol Myers Squibb, Princeton, NJ, United States.
Ian M CatlettTranslational Medicine, Immunology, Cardiovascular & Neuroscience Disease Team, Bristol Myers Squibb, Princeton, NJ, United States.
Peter SchaferTranslational Medicine, Immunology, Cardiovascular & Neuroscience Disease Team, Bristol Myers Squibb, Princeton, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Translational medicine provides insight into novel drugs and predicts unwanted effects. In well-characterized pathways (e.g., cytokine-Janus kinase [JAK]-signal transducers and activators of transcription [STAT]), a variety of

Indexed as

Janus Kinase InhibitorsAnimalsAzetidinesBridged-Ring CompoundsCytokinesHomeostasisHumansInflammationJanus KinasesPiperidinesProtein Kinase InhibitorsPurinesPyrazolesPyrimidinesPyrrolesSignal Transduction11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaeneAzetidinesbaricitinibBridged-Ring CompoundsCytokinesJanus Kinase InhibitorsJanus KinasesPiperidinesProtein Kinase InhibitorsPurinesPyrazolesPyrimidinesPyrrolesSulfonamidestofacitinibTYK2 KinasebaricitinibdeucravacitinibJAKJAK inhibitorstofacitinibTYK2upadacitinib

Identifiers

PMID39403378
PMCPMC11472182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.