Evidence map›Paper›PMID 39403377›Full record

ArticleFrontiers in immunology2024

Prevention and alleviation of allergic rhinitis by oral administration of

Xiaoli Zhou, Xizi Song, Ting Shu, Silu Zhang, Zhizhu Zhang, Canying Hu, Jie Pan, Xiaoshuang Dai, Huaijie Hao, Guoxun Xiao and 2 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. The anti-allergic effect ofFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoli Zhou *Wonderlab Innovation Centre for Healthcare, Shenzhen Porshealth Bioengineering Co., Ltd, Shenzhen, China.
Xizi Song *Department of Research and Development, Shenzhen Xbiome Biotech Co., Ltd., Shenzhen, China.
Ting ShuWonderlab Innovation Centre for Healthcare, Shenzhen Porshealth Bioengineering Co., Ltd, Shenzhen, China.
Silu ZhangWonderlab Innovation Centre for Healthcare, Shenzhen Porshealth Bioengineering Co., Ltd, Shenzhen, China.
Zhizhu ZhangWonderlab Innovation Centre for Healthcare, Shenzhen Porshealth Bioengineering Co., Ltd, Shenzhen, China.
Canying HuDepartment of Research and Development, Shenzhen Xbiome Biotech Co., Ltd., Shenzhen, China.
Jie PanDepartment of Research and Development, Shenzhen Xbiome Biotech Co., Ltd., Shenzhen, China.
Xiaoshuang DaiDepartment of Research and Development, Shenzhen Xbiome Biotech Co., Ltd., Shenzhen, China.
Huaijie HaoDepartment of Research and Development, Shenzhen Xbiome Biotech Co., Ltd., Shenzhen, China.
Guoxun XiaoWonderlab Innovation Centre for Healthcare, Shenzhen Porshealth Bioengineering Co., Ltd, Shenzhen, China.
Pengfei WangEmergency Department, Sun Yat-sen Memorial Hospital, Guangzhou, China.
Kai LiuDepartment of Rehabilitation Medicine, University of Health and Rehabilitation Sciences Qingdao Hospital (Qingdao Municipal Hospital), Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Allergic rhinitis (AR) is a widespread upper airway disorder characterized by inflammation of the nasal passages. It is immunologically mediated via the hypersensitivity type I mechanism, which is primarily elicited by the immunoglobulin E (IgE)-linking allergen-induced imbalance of the Th2/Th1 immune response. Owing to the limited efficacy of current medications, probiotics have received attention for their potential in preventing and ameliorating AR. Methods: In this study, a Results: The strain significantly attenuated the release of histamine and degranulation in LPS-induced RBL-2H3 cells. In the OVA-induced AR mice, Discussion: Furthermore, a comparison of the genomes of three previously reported AR-effective

Indexed as

CytokinesImmunoglobulin ELacticaseibacillus paracaseiProbioticsRhinitis, AllergicAdministration, OralAllergensAnimalsCell LineDisease Models, AnimalFemaleHumansMaleMiceMice, Inbred BALB CRatsAllergensCytokinesImmunoglobulin Eallergic rhinitisgene K03671immunomodulationLacticaseibacillus paracaseiprobioticTh2 immune response

Identifiers

PMID39403377
PMCPMC11472715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.