Evidence map›Paper›PMID 39402739›Full record

ArticleMagnetic resonance in medicine2025

Chemical shift-encoded multishot EPI for navigator-free prostate DWI.

Yiming Dong, David Atkinson, Kirsten Koolstra, Matthias J P van Osch, Peter Börnert

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yiming DongC.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-8580-4555
David AtkinsonCenter for Medical Imaging, University College London, London, UK.ORCID 0000-0003-1124-6666
Kirsten KoolstraPhilips, Best, The Netherlands.ORCID 0000-0002-7873-1511
Matthias J P van OschC.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-7034-8959
Peter BörnertC.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Funding

Dutch Research Council (NWO) 17104
6 · The paper itself

Abstract

purposeDWI is an important contrast for prostate MRI to enable early and accurate detection of cancer. This study introduces a Dixon 3-shot-EPI protocol with structured low-rank reconstruction for navigator-free DWI. The aim is to overcome the limitations of single-shot EPI (ssh-EPI), such as geometric distortions and fat signal interference, while addressing the motion-induced phase variations of multishot EPI and simultaneously allowing water/fat separation.

methodsDWI data were acquired from 7 healthy volunteers using both Dixon 3-shot EPI and standard fat-suppressed ssh-EPI with similar scan times for comparison. Two readers evaluated image quality using a 5-point Likert scale regarding different aspects. The ADC values were quantitatively compared between protocols. To show feasibility in a clinical setting, the protocol was applied to two patients.

resultsFrom the reader scores, Dixon 3-shot EPI significantly reduced geometric distortion compared with ssh-EPI (p < 0.01), with no significant differences in edge definition, SNR, or overall image quality. There was no significant difference in ADC values between the two protocols. However, the Dixon multishot-EPI protocol offered advantages such as self-referenced B

conclusionThe proposed Dixon 3-shot-EPI protocol shows promise as an alternative to ssh-EPI for prostate DWI, providing reduced geometric distortions and improved fat suppression. It addresses common DWI issues based on EPI and enhances scanning flexibility, indicating potential for optimized imaging.

Indexed as

Diffusion Magnetic Resonance ImagingEcho-Planar ImagingImage Interpretation, Computer-AssistedProstatic NeoplasmsAdultAlgorithmsHumansImage EnhancementMaleMiddle AgedProstateReproducibility of ResultsSensitivity and Specificitychemical shift encodingdiffusionmultishot EPIprostatestructured low rank

Identifiers

PMID39402739
PMCPMC11680737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.