Evidence map›Paper›PMID 39402650›Full record

ArticleEuropean journal of medical research2024

High levels of serum hypersensitive C-reactive protein are associated with non-alcoholic fatty liver disease in non-obese people: a cross-sectional study.

Guitao Xia, Yuemei Xu, Cheng Zhang, Mengting Li, Hongliang Li, Changxi Chen

Abstract read
In one paragraph

Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  11. The C-reactive Protein-Triglyceride-Glucose Index in Relation to Liver Disease.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guitao XiaAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China.
Yuemei XuAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China.
Cheng ZhangAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China.
Mengting LiAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China.
Hongliang LiAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China. rmlihongliang@nbu.edu.cn.
Changxi ChenAffiliated People's Hospital of Ningbo University, Ningbo, 315040, Zhejiang Province, China. rmchenchangxi@nbu.edu.cn.ORCID http://orcid.org/0000-0002-9610-1943

Funding

Ningbo Natural Science Foundation 2017A610276Science and Technology Project of Agriculture and Social Science of Ningbo Yinzhou District 2021AS0053Zhejiang Medical and Health Science and Technology Plan Project 2022KY1182
6 · The paper itself

Abstract

introductionNon-alcoholic fatty liver disease (NAFLD) and obesity have become one of the most common chronic diseases, and the global prevalence is increasing year by year. Both are accompanied by hypersensitive C-reactive protein (hs-CRP). At present, there are many predictors of NAFLD. Exploring the relationship between hs-CRP and nonalcoholic fatty liver disease in non-obese people will be helpful for risk prediction and clinical screening in high-risk populations.

objectiveTo explore the relationship between levels of serum hs-CRP and the presence of NAFLD in non-obese people.

methodsA total of 6558 participants who underwent physical examination from March 2017 to November 2017. Multivariate logistic regression was utilized to analyze the risk factors associated with NAFLD.

resultsThis study including 4240 males and 2318 females ranging from 20 to 94 years. In 1396 patients with NAFLD, the prevalence rate was 21.3%, among which 1056 (24.9%) males and 340 (14.7%) females had NAFLD. The prevalence of NAFLD was much higher in males compared to females (χ

conclusionsThe prevalence of NAFLD increases with the level of hs-CRP in both men and women who are non-obese. Hs-CRP levels are an important risk factor for nonalcoholic fatty liver disease in non-obese individuals.

Indexed as

C-Reactive ProteinNon-alcoholic Fatty Liver DiseaseAdultAgedAged, 80 and overBiomarkersBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedObesityPrevalenceRisk FactorsYoung AdultBiomarkersC-Reactive ProteinCross-sectionalHypersensitive C-reactive proteinInflammationNonalcoholic fatty liver diseaseNon-obese people

Identifiers

PMID39402650
PMCPMC11476594

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.