Evidence map›Paper›PMID 39402608›Full record

ArticleTrials2024

Telemedicine-based antibiotic stewardship program in pediatrics: study protocol of a stepped wedge cluster randomized trial-the TeleKasper study.

Sophie Diexer, Angelika Ihling, Delphina Gomes, Stefan Moritz, Arne Simon, Christian Dohna-Schwake, Rafael Mikolajczyk, Johannes Huebner, Ulrich von Both, TeleKasper Consortium

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Sophie DiexerInstitute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Medical Faculty, Interdisciplinary Centre for Health Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Angelika IhlingSection of Clinical Infectious Diseases, University Hospital Halle (Saale), Halle (Saale), Germany.
Delphina GomesInstitute of Social Pediatrics and Adolescent Medicine, Division of Pediatric Epidemiology, Ludwig-Maximilians-University Munich, Munich, Germany.
Stefan MoritzSection of Clinical Infectious Diseases, University Hospital Halle (Saale), Halle (Saale), Germany.
Arne SimonPediatric Oncology and Hematology, University Hospital Homburg Saar, Homburg, Germany.
Christian Dohna-SchwakeDepartment of Paediatrics I, Paediatric Intensive Care, Children's Hospital Essen, Essen, Germany.
Rafael MikolajczykInstitute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Medical Faculty, Interdisciplinary Centre for Health Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Johannes HuebnerDepartment of Paediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Ulrich von BothDepartment of Paediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany. Ulrich.von.both@med.lmu.de.
TeleKasper Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOveruse and misuse of antibiotics is one of the driving factors of antimicrobial resistance, a growing global health threat. The use of antibiotics is particularly high in children. Even though the implementation of antibiotic stewardship programs (ASP) in pediatrics has been shown to reduce antibiotic use, this implementation has been limited to large university hospitals in Germany. Telemedicine applications might be an effective approach to implement ASP in non-university settings.

methodsThis protocol details the TeleKasper study (Telemedical Competence Network "Antibiotic Stewardship in Pediatrics"). Tele-Kasper is a stepped-wedge cluster-randomized trial that will be conducted across non-university children's hospitals in Germany. The intervention consists of a telemedical consultation service in the form of a network in different German areas, using an app as a communication tool. The primary outcome will be a 20% reduction in overall antibiotic consumption measured using defined daily doses per 100 patient days. DISCUSSION: The TeleKasper study aims to implement and evaluate a prototype for a nationwide antibiotic stewardship program by telemedical means in pediatric departments in non-university hospitals in Germany to promote rational antibiotic use and improve medical care for infections.

trial registrationGerman Clinical Trials Register (DRKS) DRKS00028534. Registered on 22nd of April 2022.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipRandomized Controlled Trials as TopicTelemedicineChildChild, PreschoolGermanyHospitals, PediatricHumansMulticenter Studies as TopicPediatricsPractice Patterns, Physicians'Anti-Bacterial AgentsAntimicrobial stewardshipPediatricsRandomized controlled trialTelemedicine

Identifiers

PMID39402608
PMCPMC11476715

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.