Evidence map›Paper›PMID 39402460›Full record

ReviewBMC infectious diseases2024

Pregnancy-related intracranial venous sinus thrombosis secondary to cryptococcal meningoencephalitis: a case report and literature review.

Junbing He, Yufu He, Yuting Qin, Lizhen Liu, Mingwei Xu, Qinghua Liu

Abstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junbing He *Jieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China. junbingg@gdmu.edu.cn.
Yufu He *Jieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.
Yuting Qin *The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China.
Lizhen LiuThe Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, PR China.
Mingwei XuJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China.
Qinghua LiuJieyang Medical Research Center, Jieyang People's Hospital, Jieyang, Guangdong, China. liuqhua6@mail.sysu.edu.cn.

Funding

National Natural Science Foundation of China 82302446Science and Technology Innovation Leading talents Project of Jieyang City 2022SRC004Science and Technology Project of Jieyang City skjcx062
6 · The paper itself

Abstract

backgroundCerebral venous sinus thrombosis (CVST), a serious cerebrovascular and neurological emergency, is common in pregnant individuals and accounts for approximately 0.5-1.0% of all cerebrovascular diseases. However, CVST with cryptococcal meningoencephalitis in immunocompetent pregnant patients is rare. CASE PRESENTATION: A 30-year-old woman who was 33 weeks pregnant presented with recurrent dizziness, headache, and vomiting as the main clinical manifestations, all of which were initially nonspecific. After assessment of the cerebrospinal fluid, skull computerized tomography, magnetic resonance imaging, and other laboratory and imaging examinations, the patient was diagnosed with secondary pregnancy-related CVST with cryptococcal meningoencephalitis. Despite receiving potent anticoagulant and antifungal treatment, the patient's condition deteriorated, and the patient's family opted to cease treatment.

conclusionsWe present a rare case of CVST with cryptococcal meningoencephalitis in an immunocompetent pregnant patient. The difficulty of diagnosing and treating secondary pregnancy-related CVST caused by cryptococcal meningoencephalitis, as well as the great challenges faced at present are highlighted. One crucial lesson from the present case is that when clinical and imaging signs are unusual for CVST during pregnancy, it is essential to account for the possibility of other central nervous system (CNS) diseases, such as CNS infections with Cryptococcus, which may cause CVST.

Indexed as

MeningoencephalitisPregnancy Complications, InfectiousSinus Thrombosis, IntracranialAdultAntifungal AgentsCryptococcosisFemaleHumansMagnetic Resonance ImagingPregnancyTomography, X-Ray ComputedAntifungal AgentsCase reportCerebral venous sinus thrombosisCryptococcal meningoencephalitisMagnetic resonance venographyPregnancy

Identifiers

PMID39402460
PMCPMC11476198

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.