Evidence map›Paper›PMID 39402433›Full record

ArticleCardiovascular engineering and technology2025

Activation of a Soft Robotic Left Ventricular Phantom Embedded in a Closed-Loop Cardiovascular Simulator: A Computational and Experimental Analysis.

Nele Demeersseman, Maria Rocchi, Heleen Fehervary, Guillermo Fernández Collazo, Bart Meyns, Libera Fresiello, Nele Famaey

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular engineering and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Soft robotic devices for cardiovascular medicine.Nature reviews. Cardiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nele DemeerssemanBiomechanics Section, KU Leuven, Leuven, Belgium. nele.demeersseman@kuleuven.be.ORCID 0009-0001-4730-4656
Maria Rocchi *Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.ORCID 0000-0002-0046-779X
Heleen FehervaryBiomechanics Section, KU Leuven, Leuven, Belgium.ORCID 0000-0002-6908-4922
Guillermo Fernández CollazoBiomechanics Section, KU Leuven, Leuven, Belgium.ORCID 0000-0001-6502-946X
Bart MeynsDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.ORCID 0000-0002-8110-4009
Libera Fresiello *Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.ORCID 0000-0003-0972-8340
Nele Famaey *Biomechanics Section, KU Leuven, Leuven, Belgium.ORCID 0000-0002-7374-8912

Funding

Fonds Wetenschappelijk Onderzoek 1SD0321NKU Leuven C3/19/021KU Leuven C3/20/033
6 · The paper itself

Abstract

purposeCardiovascular simulators are used in the preclinical testing phase of medical devices. Their reliability increases the more they resemble clinically relevant scenarios. In this study, a physiologically actuated soft robotic left ventricle (SRLV) embedded in a hybrid (in silico- in vitro) simulator of the cardiovascular system is presented, along with its experimental and computational analysis.

methodsA SRLV phantom, developed from a patient's CT scan using polyvinyl alcohol (PVA), is embedded in a hybrid cardiovascular simulator. We present an activation method in which the hydraulic pressure external (

resultsBoth the FE model and hybrid simulator could represent the desired in silico data (

conclusionThe activation method effectively allows to represent various pressure-volume loops, as verified numerically, and validated experimentally in the hybrid simulator. This work presents a high-fidelity platform designed to simulate cardiovascular conditions, offering a robust foundation for future testing of cardiovascular medical devices under physiological conditions.

Indexed as

Computer SimulationHeart VentriclesModels, CardiovascularPhantoms, ImagingRoboticsVentricular Function, LeftEquipment DesignFinite Element AnalysisHumansReproducibility of ResultsFinite element modelingHemodynamicsHybrid cardiovascular simulatorSoft roboticsTensile testing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.