Evidence map›Paper›PMID 39402430›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Is ABO blood type a risk factor for adjacent segment degeneration after lumbar spine fusion?

Samuel S Rudisill, Dustin H Massel, Alexander L Hornung, Cameron Kia, Karan Patel, Khaled Aboushaala, Mbagwu Chukwuemeka, Arnold Y L Wong, J Nicolas Barajas, G Michael Mallow and 7 more

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Samuel S RudisillDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Dustin H MasselDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Alexander L HornungDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Cameron KiaDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Karan PatelDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Khaled AboushaalaDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Mbagwu ChukwuemekaDepartment of Orthopaedic Surgery, Louisiana State University Health, Shreveport, USA.
Arnold Y L WongThe International Spine Research and Innovation Initiative, Rush University Medical Center, Chicago, USA.
J Nicolas BarajasDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
G Michael MallowDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Sheila J ToroDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Harmanjeet SinghDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Rahul GawriDepartment of Surgery, McGill University, Montréal, Quebec, Canada.
Philip K LouieVirginia Mason Neuroscience Institute, Seattle, Washington, USA.
Frank M PhillipsDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Howard S AnDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA.
Dino SamartzisDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA. dino_samartzis@rush.edu.ORCID 0000-0002-7473-1311

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to explore associations between ABO blood type and postoperative adjacent segment degeneration/disease (ASD) following lumbar spine fusion, as well as evaluate differences in spinopelvic alignment, perioperative care, postoperative complications, and patient-reported outcome measures (PROMs).

methodsAn ambispective study was performed. Patients who underwent posterolateral or posterior lumbar interbody fusion were included. Demographic, perioperative and postoperative, clinical, and blood type information was recorded. Pre- and post-operative radiographic imaging was analyzed for alignment parameters and development of ASD.

results445 patients were included, representing O+ (36.0%), O- (5.2%), A+ (36.2%), A- (6.3%), B+ (12.1%), B- (1.6%), and AB+ (2.7%) blood types. Most patients were female (59.1%), and had a mean age of 60.3 years and BMI of 31.1 kg/m

conclusionsThis is the first large-scale study to address and demonstrate proof-of-principle that ABO blood type, a non-modifiable risk factor, is associated with ASD following lumbar spine fusion.

Indexed as

ABO Blood-Group SystemIntervertebral Disc DegenerationLumbar VertebraePostoperative ComplicationsSpinal FusionAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsABO Blood-Group SystemABOAdjacent segmentBlood typeDegenerationDiscDisease, ASD, lumbarFusionSpine

Identifiers

PMID39402430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.