Evidence map›Paper›PMID 39402376›Full record

ArticleLung2024

Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study.

Douglas Silva Queiroz, Cibele Cristine Berto Marques da Silva, Martina Rodrigues Oliveira, Alexandre Franco Amaral, Carlos Roberto Ribeiro Carvalho, João Marcos Salge, Bruno Guedes Baldi, Celso R F Carvalho

Abstract read
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In one paragraph

Article in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Douglas Silva QueirozDepartment of Physical Therapy, School of Medicine, University of Sao Paulo, São Paulo, SP, Brazil.
Cibele Cristine Berto Marques da SilvaDepartment of Physical Therapy, School of Medicine, University of Sao Paulo, São Paulo, SP, Brazil.
Martina Rodrigues OliveiraDivisão de Pneumologia, Faculdade de Medicina, Instituto Do Coração, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Alexandre Franco AmaralDivisão de Pneumologia, Faculdade de Medicina, Instituto Do Coração, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Carlos Roberto Ribeiro CarvalhoDivisão de Pneumologia, Faculdade de Medicina, Instituto Do Coração, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
João Marcos SalgeDivisão de Pneumologia, Faculdade de Medicina, Instituto Do Coração, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Bruno Guedes BaldiDivisão de Pneumologia, Faculdade de Medicina, Instituto Do Coração, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Celso R F CarvalhoDepartment of Physical Therapy, School of Medicine, University of Sao Paulo, São Paulo, SP, Brazil. cscarval@usp.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 312279/2018-3Fundação de Amparo à Pesquisa de São Paulo (FAPESP) 2018/17788-3
6 · The paper itself

Abstract

backgroundLymphangioleiomyomatosis (LAM) is a rare (twenty-one per million female inhabitants) neoplastic cystic lung disease that impairs health-related quality of life (HRQoL). However, the factors associated with impaired quality of life in patients with LAM are poorly understood.

objectiveTo assess the clinical, psychosocial, and functional characteristics associated with impaired quality of life in patients with LAM.

methodsThis was a cross-sectional study performed on two nonconsecutive days. HRQoL (SF-36 and CRQ), lung function tests, anxiety and depression symptoms (HADS), maximal (CPET and ISWT), and submaximal exercise capacity (6MWT) were assessed. Linear associations among outcomes were assessed using Pearson's correlation and multivariate tests.

resultsForty-five women with LAM (46 ± 10.years; FEV

conclusionOur results show that aerobic capacity and depression symptoms are the main factors, rather than lung function, related to quality of life in patients with LAM.

Indexed as

AnxietyDepressionExercise ToleranceLymphangioleiomyomatosisQuality of LifeAdultCross-Sectional StudiesDyspneaFatigueFemaleForced Expiratory VolumeHealth StatusHumansLungLung NeoplasmsMiddle AgedCystic lung diseaseExerciseLung functionPsychosocial aspectsQuality of life

Identifiers

PMID39402376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.