Evidence map›Paper›PMID 39402337›Full record

ArticleCommunications biology2024

FPR1 signaling aberrantly regulates S100A8/A9 production by CD14

Zhongyi Wang, Yi Wang, Qing Yan, Changlin Cai, Ying Feng, Qinghan Huang, Ting Li, Shenzhen Yuan, Juan Huang, Zhi-Hui Luo and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  6. Observational
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  11. TheFrontiers in immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhongyi Wang *Department of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Yi Wang *Department of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Qing Yan *Department of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Changlin CaiDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Ying FengDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Qinghan HuangDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Ting LiDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Shenzhen YuanDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Juan HuangDepartment of Hematology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhi-Hui LuoDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China. luozhihui@wust.edu.cn.ORCID 0000-0001-7282-4744
Jingjiao ZhouDepartment of Biology and Genetics, The College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China. zhoujj@wust.edu.cn.ORCID 0000-0003-3861-0261

Funding

Department of Science and Technology, Hubei Provincial People's Government (Hubei Provincial Department of Science and Technology) 2022EHB035Hubei Provincial Department of Education (Department of Education, Hubei Province) 1180011
6 · The paper itself

Abstract

Excessive alarmins S100A8/A9 escalate the inflammation and even exacerbate immune-driven thrombosis and multi-organ damage. However, the regulatory mechanisms of S100A8/A9 expression in infectious diseases remain unclear. In this study, high-dimensional transcriptomic data analyses revealed a high proportion of CD14

Indexed as

Calgranulin ACalgranulin BCOVID-19Lipopolysaccharide ReceptorsMacrophagesSignal TransductionAnimalsHumansLungMaleMiceMice, Inbred C57BLReceptors, Formyl PeptideSARS-CoV-2Calgranulin ACalgranulin BLipopolysaccharide ReceptorsReceptors, Formyl PeptideS100A8 protein, humanS100A9 protein, human

Identifiers

PMID39402337
PMCPMC11473795

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.