ArticleNature aging2024
SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease.
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Article in Nature aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
28 citing papers in PubMed.
- Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer's disease.Nature communications · 2026Article
- ABCC9/SUR2 has a Complex Expression Pattern in Human Brain Gliovascular Unit Cells, Including Astrocytes.Journal of molecular neuroscience : MN · 2026Article
- Temporal transcriptomic remodeling after controlled cortical impact reveals delayed AQP4/SNTA1 expression imbalance associated with ion-homeostatic remodeling.bioRxiv : the preprint server for biology · 2026Article
- Distinct single-nucleus RNA-seq changes among non-neuronal cells in ADNC, LATE-NC, and mixed pathologies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The Alzheimer's disease risk gene SORL1 is a regulator of excitatory neuronal function.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics.Nature communications · 2026Article
- Dual platform spatial transcriptomics reveals parvalbumin interneuron subtype vulnerability in mouse models of Alzheimer's disease.Nature communications · 2026Article
- Modern Mining: The Role of Single-cell RNA Sequencing in Advancing Neuroscience Research.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Reproducibility-driven discovery and systematic benchmarking reveal a robust cerebrospinal fluid proteomic signature in Alzheimer's disease.medRxiv : the preprint server for health sciences · 2026Article
- Lactate metabolism links reactive microglia, amyloid pathology, and Aβ dynamics.Journal of neuroinflammation · 2026Article
- A Community Standard Multispecies Cell Atlas of the Basal Ganglia.bioRxiv : the preprint server for biology · 2026Article
- Early microglial priming in Alzheimer's disease revealed by ME-seq.bioRxiv : the preprint server for biology · 2026Article
- Article
- Reply to: a quantitative trait locus for reduced microglial APOE expression associates with reduced cerebral amyloid angiopathy.Nature genetics · 2026Article
- From the brain cell atlas to precision neurology: a review of the application of AI-driven multi-omics in brain science.GigaScience · 2026Review
- Neuroimmune Dysregulation and AI-Driven Therapeutic Strategies in Alzheimer's Disease.Cellular and molecular neurobiology · 2025Review
- Single-cell landscape of sex-specific drivers of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Ferroptosis-associated transcriptional factors in neurological diseases: molecular mechanisms and therapeutic prospects.Experimental & molecular medicine · 2025Review
- The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks.Journal of neurochemistry · 2025Review
- Review
Corrections and comments
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Authors and funding
17 authors.
Michael HawrylyczAllen Institute for Brain Science, Seattle, WA, USA. mikeh@alleninstitute.org.
Eitan S KaplanAllen Institute for Brain Science, Seattle, WA, USA.
Kyle J TravagliniAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3164-6448
Mariano I GabittoAllen Institute for Brain Science, Seattle, WA, USA.
Jeremy A MillerAllen Institute for Brain Science, Seattle, WA, USA.
Lydia NgAllen Institute for Brain Science, Seattle, WA, USA.
Jennie L CloseAllen Institute for Brain Science, Seattle, WA, USA.
Rebecca D HodgeAllen Institute for Brain Science, Seattle, WA, USA.
Brian LongAllen Institute for Brain Science, Seattle, WA, USA.
Tyler MollenkopfAllen Institute for Brain Science, Seattle, WA, USA.
Shoaib MuftiAllen Institute for Brain Science, Seattle, WA, USA.
Nicole M GattoKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Eric B LarsonDepartment of Medicine, University of Washington, Seattle, WA, USA.
Paul K CraneDepartment of Medicine, University of Washington, Seattle, WA, USA.
Thomas J GrabowskiDepartment of Radiology, University of Washington, Seattle, WA, USA.
C Dirk KeeneDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5291-1469
Ed S LeinAllen Institute for Brain Science, Seattle, WA, USA. edl@alleninstitute.org.ORCID http://orcid.org/0000-0001-9012-6552
Funding
Topographic, cell type and molecular pathway characterization ofAlzheimer's disease using single cell transcriptomics and epigenomicsU19AG060909 · NIA · ALLEN INSTITUTE · PI Jennie Leigh Close, Michael Hawrylycz · 2020 to 2026
$83.6MTranslational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Paul K Crane, Andrea Z. LaCroix · 2021 to 2026
$80.4MTHERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI JAYADEY, SUMAN · 1985 to 2019
$57.2MFurthering scientific understanding of mechanisms underlying resilience to the effects of AD pathology by incorporating state of the art quantification of gliosis, inflammation, & synaptic toxicityU01AG006781 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K, LARSON, ERIC B · 1986 to 2020
$39.3MUniversity of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI SUMAN JAYADEV · 2020 to 2026
$29.0MNIA NIH HHS P30 AG066509NIA NIH HHS P50 AG005136NIA NIH HHS U01 AG006781NIA NIH HHS U19 AG060909NIA NIH HHS U19 AG066567U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) P30AG066509U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) P50AG005136U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U01AG006781U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U19AG060909U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U19AG066567
Abstract
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.