Evidence map›Paper›PMID 39402236›Full record

ArticleNature microbiology2024

Genomic and functional characterization of the Atlantic salmon gut microbiome in relation to nutrition and health.

Arturo Vera-Ponce de León, Tim Hensen, Matthias Hoetzinger, Shashank Gupta, Bronson Weston, Sander M Johnsen, Jacob A Rasmussen, Cecilie Grønlund Clausen, Louisa Pless, Ana Raquel Andrade Veríssimo and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Biodegradation of components from an oxidized polyethylene by aApplied and environmental microbiology · 2026
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  7. mBio · 2025
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Arturo Vera-Ponce de LeónFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.ORCID http://orcid.org/0000-0003-4085-5700
Tim HensenSchool of Medicine, University of Galway, Galway, Ireland.
Matthias HoetzingerFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Shashank GuptaFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Bronson WestonSchool of Medicine, University of Galway, Galway, Ireland.
Sander M JohnsenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Jacob A RasmussenCenter for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-7710-8912
Cecilie Grønlund ClausenCenter for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Louisa PlessCenter for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Ana Raquel Andrade VeríssimoCenter for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Knut RudiFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Lars SnipenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Christian René KarlsenDepartment of Fish Health, Nofima, Tromsø, Norway.
Morten T LimborgCenter for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-7718-6531
Stefan BertilssonDepartment of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-4265-1835
Ines ThieleSchool of Medicine, University of Galway, Galway, Ireland.
Torgeir R HvidstenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.ORCID http://orcid.org/0000-0001-6097-2539
Simen R SandveFaculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Phillip B Pope *Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway. phil.pope@nmbu.no.ORCID http://orcid.org/0000-0002-2067-4059
Sabina Leanti La Rosa *Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway. sabina.leantilarosa@nmbu.no.ORCID http://orcid.org/0000-0003-3527-8101

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 757922Norges Forskningsråd (Research Council of Norway) 300846Science Foundation Ireland (SFI) 12/RC/2273-P2
6 · The paper itself

Abstract

To ensure sustainable aquaculture, it is essential to understand the path 'from feed to fish', whereby the gut microbiome plays an important role in digestion and metabolism, ultimately influencing host health and growth. Previous work has reported the taxonomic composition of the Atlantic salmon (Salmo salar) gut microbiome; however, functional insights are lacking. Here we present the Salmon Microbial Genome Atlas consisting of 211 high-quality bacterial genomes, recovered by cultivation (n = 131) and gut metagenomics (n = 80) from wild and farmed fish both in freshwater and seawater. Bacterial genomes were taxonomically assigned to 14 different orders, including 35 distinctive genera and 29 previously undescribed species. Using metatranscriptomics, we functionally characterized key bacterial populations, across five phyla, in the salmon gut. This included the ability to degrade diet-derived fibres and release vitamins and other exometabolites with known beneficial effects, which was supported by genome-scale metabolic modelling and in vitro cultivation of selected bacterial species coupled with untargeted metabolomic studies. Together, the Salmon Microbial Genome Atlas provides a genomic and functional resource to enable future studies on salmon nutrition and health.

Indexed as

AquacultureBacteriaGastrointestinal MicrobiomeGenome, BacterialMetagenomicsSalmo salarAnimalsFresh WaterGenomicsPhylogenySeawater

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.